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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CST1 All Species: 4.24
Human Site: T77 Identified Species: 11.67
UniProt: P01037 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01037 NP_001889.2 141 16362 T77 V L R A R Q Q T V G G V N Y F
Chimpanzee Pan troglodytes XP_001147590 158 18123 T94 V L R A R Q Q T V E G V N F F
Rhesus Macaque Macaca mulatta O19092 146 15839 I82 V V R A R K Q I V A G V N Y F
Dog Lupus familis XP_848294 141 16619 V77 V L K S Q E Q V T E S L D Y F
Cat Felis silvestris
Mouse Mus musculus P21460 140 15512 L76 V V R A R K Q L V A G V N Y F
Rat Rattus norvegicus P14841 140 15418 L76 V V R A R K Q L V A G I N Y Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518631 78 8921 A16 Q E E K E I V A G V K Y Y L D
Chicken Gallus gallus P01038 139 15268 L77 V I S A K R Q L V S G I K Y I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001026843 128 14125 Q66 K V T K L Q K Q V V A G I K Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.4 56.1 29.7 N.A. 56 53.1 N.A. 29 40.4 N.A. 29.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 87.9 70.5 56.7 N.A. 70.9 70.9 N.A. 41.1 61.7 N.A. 51 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 86.6 73.3 33.3 N.A. 73.3 60 N.A. 0 40 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 86.6 73.3 N.A. 86.6 86.6 N.A. 0 66.6 N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 67 0 0 0 12 0 34 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 12 % D
% Glu: 0 12 12 0 12 12 0 0 0 23 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 56 % F
% Gly: 0 0 0 0 0 0 0 0 12 12 67 12 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 12 0 0 0 12 0 12 0 0 0 23 12 0 12 % I
% Lys: 12 0 12 23 12 34 12 0 0 0 12 0 12 12 0 % K
% Leu: 0 34 0 0 12 0 0 34 0 0 0 12 0 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 56 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 12 0 0 0 12 34 78 12 0 0 0 0 0 0 0 % Q
% Arg: 0 0 56 0 56 12 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 12 12 0 0 0 0 0 12 12 0 0 0 0 % S
% Thr: 0 0 12 0 0 0 0 23 12 0 0 0 0 0 0 % T
% Val: 78 45 0 0 0 0 12 12 78 23 0 45 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 12 12 67 23 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _