Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CST1 All Species: 4.55
Human Site: Y35 Identified Species: 12.5
UniProt: P01037 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01037 NP_001889.2 141 16362 Y35 R I I P G G I Y N A D L N D E
Chimpanzee Pan troglodytes XP_001147590 158 18123 Y52 R I I P G G I Y N A D L N D E
Rhesus Macaque Macaca mulatta O19092 146 15839 M40 P R L V G G P M D A S V E E E
Dog Lupus familis XP_848294 141 16619 Q35 S K V V R T F Q D I P E T Y V
Cat Felis silvestris
Mouse Mus musculus P21460 140 15512 E35 R M L G A P E E A D A N E E G
Rat Rattus norvegicus P14841 140 15418 E35 R L L G A P Q E A D A S E E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518631 78 8921
Chicken Gallus gallus P01038 139 15268 V35 S R L L G A P V P V D E N D E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001026843 128 14125 D27 G L V G G P T D A D M D K D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.4 56.1 29.7 N.A. 56 53.1 N.A. 29 40.4 N.A. 29.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 87.9 70.5 56.7 N.A. 70.9 70.9 N.A. 41.1 61.7 N.A. 51 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 26.6 0 N.A. 6.6 6.6 N.A. 0 33.3 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 53.3 13.3 N.A. 26.6 26.6 N.A. 0 40 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 23 12 0 0 34 34 23 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 12 23 34 34 12 0 45 0 % D
% Glu: 0 0 0 0 0 0 12 23 0 0 0 23 34 34 45 % E
% Phe: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % F
% Gly: 12 0 0 34 56 34 0 0 0 0 0 0 0 0 23 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 23 23 0 0 0 23 0 0 12 0 0 0 0 0 % I
% Lys: 0 12 0 0 0 0 0 0 0 0 0 0 12 0 0 % K
% Leu: 0 23 45 12 0 0 0 0 0 0 0 23 0 0 0 % L
% Met: 0 12 0 0 0 0 0 12 0 0 12 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 23 0 0 12 34 0 0 % N
% Pro: 12 0 0 23 0 34 23 0 12 0 12 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 12 12 0 0 0 0 0 0 0 % Q
% Arg: 45 23 0 0 12 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 23 0 0 0 0 0 0 0 0 0 12 12 0 0 12 % S
% Thr: 0 0 0 0 0 12 12 0 0 0 0 0 12 0 0 % T
% Val: 0 0 23 23 0 0 0 12 0 12 0 12 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 23 0 0 0 0 0 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _