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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CST1
All Species:
4.55
Human Site:
Y35
Identified Species:
12.5
UniProt:
P01037
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01037
NP_001889.2
141
16362
Y35
R
I
I
P
G
G
I
Y
N
A
D
L
N
D
E
Chimpanzee
Pan troglodytes
XP_001147590
158
18123
Y52
R
I
I
P
G
G
I
Y
N
A
D
L
N
D
E
Rhesus Macaque
Macaca mulatta
O19092
146
15839
M40
P
R
L
V
G
G
P
M
D
A
S
V
E
E
E
Dog
Lupus familis
XP_848294
141
16619
Q35
S
K
V
V
R
T
F
Q
D
I
P
E
T
Y
V
Cat
Felis silvestris
Mouse
Mus musculus
P21460
140
15512
E35
R
M
L
G
A
P
E
E
A
D
A
N
E
E
G
Rat
Rattus norvegicus
P14841
140
15418
E35
R
L
L
G
A
P
Q
E
A
D
A
S
E
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518631
78
8921
Chicken
Gallus gallus
P01038
139
15268
V35
S
R
L
L
G
A
P
V
P
V
D
E
N
D
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001026843
128
14125
D27
G
L
V
G
G
P
T
D
A
D
M
D
K
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
56.1
29.7
N.A.
56
53.1
N.A.
29
40.4
N.A.
29.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
87.9
70.5
56.7
N.A.
70.9
70.9
N.A.
41.1
61.7
N.A.
51
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
26.6
0
N.A.
6.6
6.6
N.A.
0
33.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
53.3
13.3
N.A.
26.6
26.6
N.A.
0
40
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
23
12
0
0
34
34
23
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
23
34
34
12
0
45
0
% D
% Glu:
0
0
0
0
0
0
12
23
0
0
0
23
34
34
45
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
34
56
34
0
0
0
0
0
0
0
0
23
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
23
23
0
0
0
23
0
0
12
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
0
0
12
0
0
% K
% Leu:
0
23
45
12
0
0
0
0
0
0
0
23
0
0
0
% L
% Met:
0
12
0
0
0
0
0
12
0
0
12
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
23
0
0
12
34
0
0
% N
% Pro:
12
0
0
23
0
34
23
0
12
0
12
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
12
12
0
0
0
0
0
0
0
% Q
% Arg:
45
23
0
0
12
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
23
0
0
0
0
0
0
0
0
0
12
12
0
0
12
% S
% Thr:
0
0
0
0
0
12
12
0
0
0
0
0
12
0
0
% T
% Val:
0
0
23
23
0
0
0
12
0
12
0
12
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
23
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _