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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSTA All Species: 27.27
Human Site: T45 Identified Species: 85.71
UniProt: P01040 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01040 NP_005204.1 98 11006 T45 L E A V Q Y K T Q V V A G T N
Chimpanzee Pan troglodytes Q8I030 98 11135 S45 F K A V S F K S Q V V A G T N
Rhesus Macaque Macaca mulatta XP_001112115 98 11039 T45 L E A V E Y K T Q V V A G I N
Dog Lupus familis XP_545130 369 40655 T316 F E A V E Y K T Q V V A G I N
Cat Felis silvestris
Mouse Mus musculus P56567 97 10911 T45 F K A V E Y K T Q V V A G V N
Rat Rattus norvegicus P01039 103 11545 S51 F K V V E Y K S Q V V A G Q I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516860 99 11205 T45 Y E A L E F K T Q V V A G V N
Chicken Gallus gallus XP_416492 98 11141 T45 F T A V E F K T Q L V A G T N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53 92.8 21.9 N.A. 63.2 56.3 N.A. 65.6 57.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 72.4 95.9 23.8 N.A. 78.5 72.8 N.A. 79.8 78.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 66.6 86.6 80 N.A. 73.3 53.3 N.A. 66.6 66.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 86.6 93.3 86.6 N.A. 86.6 73.3 N.A. 86.6 86.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 88 0 0 0 0 0 0 0 0 100 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 50 0 0 75 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 63 0 0 0 0 38 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 13 % I
% Lys: 0 38 0 0 0 0 100 0 0 0 0 0 0 0 0 % K
% Leu: 25 0 0 13 0 0 0 0 0 13 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 13 0 0 0 100 0 0 0 0 13 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 13 0 0 25 0 0 0 0 0 0 0 % S
% Thr: 0 13 0 0 0 0 0 75 0 0 0 0 0 38 0 % T
% Val: 0 0 13 88 0 0 0 0 0 88 100 0 0 25 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 0 0 0 0 63 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _