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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NRAS All Species: 41.21
Human Site: Y96 Identified Species: 90.67
UniProt: P01111 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01111 NP_002515.1 189 21229 Y96 S F A D I N L Y R E Q I K R V
Chimpanzee Pan troglodytes XP_521702 189 21289 Y96 S F E D I H Q Y R E Q I K R V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540523 226 24555 Y133 S F E D I H Q Y R E Q I K R V
Cat Felis silvestris
Mouse Mus musculus P08556 189 21181 Y96 S F A D I N L Y R E Q I K R V
Rat Rattus norvegicus Q04970 189 21225 Y96 S F A D I N L Y R E Q I K R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F352 189 21260 Y96 S F A D I N L Y R E Q I K R V
Frog Xenopus laevis Q91806 189 21364 Y96 S F A D I N A Y R E Q I K R V
Zebra Danio Brachydanio rerio P79737 188 21321 Y96 S F A D V H L Y R E Q I K R V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08646 189 21575 Y96 S F E D I G T Y R E Q I K R V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P22981 184 20964 Y96 S F E N V A N Y R E Q I R R V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P22126 213 24008 Y101 S F E E I R I Y Q Q Q I L R V
Conservation
Percent
Protein Identity: 100 84.6 N.A. 70.8 N.A. 98.4 99.4 N.A. N.A. 96.8 92.5 90.4 N.A. 75.6 N.A. 74 N.A.
Protein Similarity: 100 92 N.A. 77.8 N.A. 99.4 100 N.A. N.A. 98.4 96.3 94.1 N.A. 84.6 N.A. 85.1 N.A.
P-Site Identity: 100 80 N.A. 80 N.A. 100 100 N.A. N.A. 100 93.3 86.6 N.A. 80 N.A. 60 N.A.
P-Site Similarity: 100 86.6 N.A. 86.6 N.A. 100 100 N.A. N.A. 100 93.3 100 N.A. 80 N.A. 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 57.7
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 70.4
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 53.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 55 0 0 10 10 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 82 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 46 10 0 0 0 0 0 91 0 0 0 0 0 % E
% Phe: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 28 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 82 0 10 0 0 0 0 100 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 82 0 0 % K
% Leu: 0 0 0 0 0 0 46 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 46 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 19 0 10 10 100 0 0 0 0 % Q
% Arg: 0 0 0 0 0 10 0 0 91 0 0 0 10 100 0 % R
% Ser: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 100 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _