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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EGF
All Species:
13.03
Human Site:
S1075
Identified Species:
31.85
UniProt:
P01133
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01133
NP_001954.2
1207
133994
S1075
K
N
P
Y
E
E
S
S
R
D
V
R
S
R
R
Chimpanzee
Pan troglodytes
XP_517395
1207
133852
S1075
K
N
P
Y
E
E
S
S
R
D
V
R
S
R
R
Rhesus Macaque
Macaca mulatta
XP_001088957
1208
133544
S1075
K
N
P
S
E
E
S
S
R
D
A
R
S
H
R
Dog
Lupus familis
XP_540748
2021
223644
I1695
T
D
W
Q
T
K
S
I
Q
R
V
D
K
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
P01132
1217
133126
S1081
K
N
P
C
D
E
P
S
G
S
V
S
S
S
G
Rat
Rattus norvegicus
P07522
1133
124107
W1023
Q
H
R
D
L
R
W
W
K
L
R
H
A
D
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001001292
1245
138103
I1124
K
N
R
Y
A
E
V
I
R
D
A
S
S
H
T
Frog
Xenopus laevis
Q99088
892
99806
T783
K
T
T
L
R
M
N
T
E
K
V
P
A
H
T
Zebra Danio
Brachydanio rerio
NP_991294
1114
121901
S1005
G
G
C
S
L
Q
D
S
V
G
E
M
S
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782472
780
86184
V671
R
L
L
Y
T
Y
I
V
V
G
V
L
A
F
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.5
20.2
N.A.
65.8
63.6
N.A.
N.A.
50.4
20.2
37.5
N.A.
N.A.
N.A.
N.A.
22.6
Protein Similarity:
100
99.3
96.1
32.4
N.A.
78.4
75.8
N.A.
N.A.
65.6
34.7
55
N.A.
N.A.
N.A.
N.A.
36.3
P-Site Identity:
100
100
80
13.3
N.A.
46.6
0
N.A.
N.A.
46.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
80
33.3
N.A.
53.3
26.6
N.A.
N.A.
46.6
33.3
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
20
0
30
10
0
% A
% Cys:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
10
0
10
0
0
40
0
10
0
10
0
% D
% Glu:
0
0
0
0
30
50
0
0
10
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
10
10
0
0
0
0
0
0
10
20
0
0
0
0
10
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
10
0
30
0
% H
% Ile:
0
0
0
0
0
0
10
20
0
0
0
0
0
0
0
% I
% Lys:
60
0
0
0
0
10
0
0
10
10
0
0
10
0
0
% K
% Leu:
0
10
10
10
20
0
0
0
0
10
0
10
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
50
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
40
0
0
0
10
0
0
0
0
10
0
0
0
% P
% Gln:
10
0
0
10
0
10
0
0
10
0
0
0
0
0
0
% Q
% Arg:
10
0
20
0
10
10
0
0
40
10
10
30
0
20
30
% R
% Ser:
0
0
0
20
0
0
40
50
0
10
0
20
60
10
20
% S
% Thr:
10
10
10
0
20
0
0
10
0
0
0
0
0
0
20
% T
% Val:
0
0
0
0
0
0
10
10
20
0
60
0
0
0
10
% V
% Trp:
0
0
10
0
0
0
10
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
40
0
10
0
0
0
0
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _