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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EGF
All Species:
7.58
Human Site:
S1125
Identified Species:
18.52
UniProt:
P01133
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01133
NP_001954.2
1207
133994
S1125
D
G
Q
A
A
D
G
S
M
Q
P
T
S
W
R
Chimpanzee
Pan troglodytes
XP_517395
1207
133852
S1125
D
G
Q
A
A
D
G
S
M
Q
P
T
S
W
R
Rhesus Macaque
Macaca mulatta
XP_001088957
1208
133544
S1126
G
Q
A
A
D
V
G
S
V
Q
P
T
S
W
R
Dog
Lupus familis
XP_540748
2021
223644
P1898
E
V
K
I
E
A
I
P
K
P
A
M
Y
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
P01132
1217
133126
L1139
G
L
S
P
S
L
Q
L
G
S
V
H
L
T
S
Rat
Rattus norvegicus
P07522
1133
124107
G1056
L
L
L
L
G
M
W
G
T
Y
Y
Y
R
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001001292
1245
138103
K1158
C
S
S
A
L
E
T
K
V
L
D
L
I
E
C
Frog
Xenopus laevis
Q99088
892
99806
R815
A
G
V
V
E
S
A
R
S
H
P
T
A
L
Y
Zebra Danio
Brachydanio rerio
NP_991294
1114
121901
A1037
L
D
T
S
T
C
T
A
D
K
V
L
H
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782472
780
86184
E703
L
P
N
K
L
N
N
E
E
L
D
R
M
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.5
20.2
N.A.
65.8
63.6
N.A.
N.A.
50.4
20.2
37.5
N.A.
N.A.
N.A.
N.A.
22.6
Protein Similarity:
100
99.3
96.1
32.4
N.A.
78.4
75.8
N.A.
N.A.
65.6
34.7
55
N.A.
N.A.
N.A.
N.A.
36.3
P-Site Identity:
100
100
60
0
N.A.
0
6.6
N.A.
N.A.
6.6
20
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
66.6
20
N.A.
6.6
6.6
N.A.
N.A.
20
26.6
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
40
20
10
10
10
0
0
10
0
10
0
0
% A
% Cys:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% C
% Asp:
20
10
0
0
10
20
0
0
10
0
20
0
0
0
0
% D
% Glu:
10
0
0
0
20
10
0
10
10
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
20
30
0
0
10
0
30
10
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
10
10
0
0
% H
% Ile:
0
0
0
10
0
0
10
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
10
10
0
0
0
10
10
10
0
0
0
0
0
% K
% Leu:
30
20
10
10
20
10
0
10
0
20
0
20
10
20
0
% L
% Met:
0
0
0
0
0
10
0
0
20
0
0
10
10
0
0
% M
% Asn:
0
0
10
0
0
10
10
0
0
0
0
0
0
10
0
% N
% Pro:
0
10
0
10
0
0
0
10
0
10
40
0
0
0
10
% P
% Gln:
0
10
20
0
0
0
10
0
0
30
0
0
0
0
20
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
10
10
0
40
% R
% Ser:
0
10
20
10
10
10
0
30
10
10
0
0
30
0
10
% S
% Thr:
0
0
10
0
10
0
20
0
10
0
0
40
0
20
0
% T
% Val:
0
10
10
10
0
10
0
0
20
0
20
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
30
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
10
10
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _