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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EGF
All Species:
12.12
Human Site:
S1169
Identified Species:
29.63
UniProt:
P01133
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01133
NP_001954.2
1207
133994
S1169
E
R
S
F
H
M
P
S
Y
G
T
Q
T
L
E
Chimpanzee
Pan troglodytes
XP_517395
1207
133852
S1169
E
R
S
F
H
M
P
S
Y
G
T
Q
T
L
E
Rhesus Macaque
Macaca mulatta
XP_001088957
1208
133544
S1170
E
R
S
F
H
M
P
S
Y
G
T
R
P
V
D
Dog
Lupus familis
XP_540748
2021
223644
L1942
D
D
A
E
W
D
D
L
K
Q
L
R
S
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P01132
1217
133126
S1183
E
G
N
S
H
L
P
S
Y
R
P
V
G
P
E
Rat
Rattus norvegicus
P07522
1133
124107
W1100
V
S
S
G
P
Q
P
W
F
V
V
L
E
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001001292
1245
138103
P1202
E
K
K
E
Q
G
C
P
E
D
V
P
S
T
E
Frog
Xenopus laevis
Q99088
892
99806
Y859
I
N
F
D
N
P
V
Y
Q
K
T
T
E
E
D
Zebra Danio
Brachydanio rerio
NP_991294
1114
121901
I1081
G
C
S
L
A
V
A
I
C
S
V
S
C
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782472
780
86184
N747
R
P
C
E
K
P
K
N
T
N
L
N
A
C
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.5
20.2
N.A.
65.8
63.6
N.A.
N.A.
50.4
20.2
37.5
N.A.
N.A.
N.A.
N.A.
22.6
Protein Similarity:
100
99.3
96.1
32.4
N.A.
78.4
75.8
N.A.
N.A.
65.6
34.7
55
N.A.
N.A.
N.A.
N.A.
36.3
P-Site Identity:
100
100
73.3
0
N.A.
40
13.3
N.A.
N.A.
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
26.6
N.A.
53.3
20
N.A.
N.A.
26.6
20
13.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
10
0
0
0
0
0
10
0
0
% A
% Cys:
0
10
10
0
0
0
10
0
10
0
0
0
10
10
0
% C
% Asp:
10
10
0
10
0
10
10
0
0
10
0
0
0
10
20
% D
% Glu:
50
0
0
30
0
0
0
0
10
0
0
0
20
20
40
% E
% Phe:
0
0
10
30
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
10
10
0
10
0
10
0
0
0
30
0
0
10
0
0
% G
% His:
0
0
0
0
40
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% I
% Lys:
0
10
10
0
10
0
10
0
10
10
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
10
0
10
0
0
20
10
0
20
0
% L
% Met:
0
0
0
0
0
30
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
10
0
0
10
0
10
0
10
0
0
0
% N
% Pro:
0
10
0
0
10
20
50
10
0
0
10
10
10
10
0
% P
% Gln:
0
0
0
0
10
10
0
0
10
10
0
20
0
0
0
% Q
% Arg:
10
30
0
0
0
0
0
0
0
10
0
20
0
0
10
% R
% Ser:
0
10
50
10
0
0
0
40
0
10
0
10
20
10
10
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
40
10
20
10
0
% T
% Val:
10
0
0
0
0
10
10
0
0
10
30
10
0
10
0
% V
% Trp:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
40
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _