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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGFA
All Species:
17.88
Human Site:
S144
Identified Species:
43.7
UniProt:
P01135
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01135
NP_003227.1
160
17006
S144
I
C
R
H
E
K
P
S
A
L
L
K
G
R
T
Chimpanzee
Pan troglodytes
XP_001142732
163
17382
S144
I
C
R
H
E
K
P
S
A
L
L
K
G
R
T
Rhesus Macaque
Macaca mulatta
P55244
121
13164
H106
H
C
C
Q
V
R
K
H
C
E
W
C
R
A
L
Dog
Lupus familis
XP_855490
479
49302
S259
L
C
R
H
E
K
P
S
A
L
L
K
G
R
A
Cat
Felis silvestris
Mouse
Mus musculus
P48030
159
17000
S143
V
C
R
H
E
K
P
S
A
L
L
K
G
R
T
Rat
Rattus norvegicus
P01134
159
16942
S143
V
C
R
H
E
K
P
S
A
L
L
K
G
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519544
101
10704
V86
T
I
T
A
L
L
V
V
S
V
L
A
S
V
T
Chicken
Gallus gallus
Q5EG71
151
17011
C135
Y
C
Y
V
R
K
R
C
R
K
L
K
S
P
Y
Frog
Xenopus laevis
NP_001088773
160
17166
G144
F
C
Q
H
E
K
P
G
S
F
L
K
G
G
V
Zebra Danio
Brachydanio rerio
NP_001137524
191
21204
V174
N
S
E
T
G
I
P
V
L
H
F
H
F
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
74.3
29.6
N.A.
91.8
92.5
N.A.
45.6
29.3
73.1
33.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.5
75
31.1
N.A.
95.6
96.2
N.A.
53.7
43.1
85
46
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
86.6
N.A.
93.3
93.3
N.A.
13.3
26.6
53.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
93.3
N.A.
100
100
N.A.
26.6
26.6
66.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
50
0
0
10
0
10
10
% A
% Cys:
0
80
10
0
0
0
0
10
10
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
60
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
10
10
0
10
0
0
% F
% Gly:
0
0
0
0
10
0
0
10
0
0
0
0
60
10
0
% G
% His:
10
0
0
60
0
0
0
10
0
10
0
10
0
0
0
% H
% Ile:
20
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
70
10
0
0
10
0
70
0
0
0
% K
% Leu:
10
0
0
0
10
10
0
0
10
50
80
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
70
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
50
0
10
10
10
0
10
0
0
0
10
50
0
% R
% Ser:
0
10
0
0
0
0
0
50
20
0
0
0
20
0
0
% S
% Thr:
10
0
10
10
0
0
0
0
0
0
0
0
0
0
60
% T
% Val:
20
0
0
10
10
0
10
20
0
10
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
10
0
10
0
0
0
0
0
0
0
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _