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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGF
All Species:
19.7
Human Site:
S22
Identified Species:
48.15
UniProt:
P01138
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01138
NP_002497.2
241
26959
S22
G
I
Q
A
E
P
H
S
E
S
N
V
P
A
G
Chimpanzee
Pan troglodytes
Q9N2F1
241
26869
S22
G
T
Q
A
E
P
H
S
E
S
N
V
P
A
G
Rhesus Macaque
Macaca mulatta
XP_001100522
403
45219
S184
G
I
Q
A
E
P
H
S
E
S
N
V
P
A
G
Dog
Lupus familis
XP_540250
543
59900
P324
G
I
R
A
E
P
H
P
E
S
H
V
P
A
G
Cat
Felis silvestris
Mouse
Mus musculus
P01139
241
27058
T22
G
V
Q
A
E
P
Y
T
D
S
N
V
P
E
G
Rat
Rattus norvegicus
P25427
241
26991
T22
G
V
Q
A
E
P
Y
T
D
S
N
V
P
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507118
180
20438
Chicken
Gallus gallus
P05200
243
27119
S26
G
T
Q
A
A
P
K
S
E
D
N
G
P
L
E
Frog
Xenopus laevis
P21617
231
26398
V16
L
I
A
I
L
I
S
V
Q
A
A
P
K
T
K
Zebra Danio
Brachydanio rerio
NP_954680
194
21884
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
59
40.7
N.A.
85
85.8
N.A.
39.8
64.1
61.4
44.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
59
41.4
N.A.
90.8
91.6
N.A.
51.4
72.4
74.6
56
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
80
N.A.
66.6
66.6
N.A.
0
53.3
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
93.3
N.A.
93.3
93.3
N.A.
0
53.3
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
70
10
0
0
0
0
10
10
0
0
40
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
20
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
60
0
0
0
50
0
0
0
0
20
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
70
0
0
0
0
0
0
0
0
0
0
10
0
0
60
% G
% His:
0
0
0
0
0
0
40
0
0
0
10
0
0
0
0
% H
% Ile:
0
40
0
10
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
10
% K
% Leu:
10
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
60
0
0
0
0
% N
% Pro:
0
0
0
0
0
70
0
10
0
0
0
10
70
0
0
% P
% Gln:
0
0
60
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
40
0
60
0
0
0
0
0
% S
% Thr:
0
20
0
0
0
0
0
20
0
0
0
0
0
10
0
% T
% Val:
0
20
0
0
0
0
0
10
0
0
0
60
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _