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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POMC
All Species:
22.12
Human Site:
Y139
Identified Species:
60.83
UniProt:
P01189
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01189
NP_000930.1
267
29424
Y139
P
R
E
G
K
R
S
Y
S
M
E
H
F
R
W
Chimpanzee
Pan troglodytes
XP_515334
268
29530
Y140
P
R
E
G
K
R
S
Y
S
M
E
H
F
R
W
Rhesus Macaque
Macaca mulatta
XP_001082745
265
29146
Y137
P
R
E
G
K
R
S
Y
S
M
E
H
F
R
W
Dog
Lupus familis
XP_849463
247
27106
M137
E
G
K
R
S
Y
S
M
E
H
F
R
W
G
K
Cat
Felis silvestris
Mouse
Mus musculus
P01193
235
26689
Y125
P
R
E
G
K
R
S
Y
S
M
E
H
F
R
W
Rat
Rattus norvegicus
P01194
235
26521
Y125
P
R
E
G
K
R
S
Y
S
M
E
H
F
R
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026269
251
28170
H137
K
R
S
Y
S
M
E
H
F
R
W
G
K
P
V
Frog
Xenopus laevis
P06298
259
29860
Y141
R
Q
E
N
K
R
A
Y
S
M
E
H
F
R
W
Zebra Danio
Brachydanio rerio
NP_852103
222
25494
M111
D
H
K
R
S
Y
S
M
E
H
F
R
W
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94.3
76.7
N.A.
73.4
71.5
N.A.
N.A.
53.5
55.4
43.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.5
96.6
83.5
N.A.
79.4
79
N.A.
N.A.
68.1
70.4
55.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
6.6
73.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
N.A.
13.3
86.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
12
0
67
0
0
0
12
0
23
0
67
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
23
0
67
0
0
% F
% Gly:
0
12
0
56
0
0
0
0
0
0
0
12
0
23
0
% G
% His:
0
12
0
0
0
0
0
12
0
23
0
67
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
23
0
67
0
0
0
0
0
0
0
12
0
23
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
12
0
23
0
67
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
56
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% P
% Gln:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
67
0
23
0
67
0
0
0
12
0
23
0
67
0
% R
% Ser:
0
0
12
0
34
0
78
0
67
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
12
0
23
0
67
% W
% Tyr:
0
0
0
12
0
23
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _