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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PENK
All Species:
21.82
Human Site:
S153
Identified Species:
53.33
UniProt:
P01210
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01210
NP_001129162.1
267
30787
S153
E
D
D
S
L
A
N
S
S
D
L
L
K
E
L
Chimpanzee
Pan troglodytes
XP_001155627
267
30741
S153
E
D
D
S
L
A
N
S
S
D
L
L
K
E
L
Rhesus Macaque
Macaca mulatta
XP_001113720
253
27992
E141
G
G
F
G
E
G
A
E
S
E
L
M
R
D
A
Dog
Lupus familis
XP_535081
254
28765
S142
E
D
V
L
A
N
S
S
D
L
L
K
E
L
L
Cat
Felis silvestris
Mouse
Mus musculus
P22005
268
30986
S153
E
G
D
T
L
A
N
S
S
D
L
L
K
E
L
Rat
Rattus norvegicus
P04094
269
30913
S153
E
G
D
T
L
A
N
S
S
D
L
L
K
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513911
267
29807
S153
D
D
E
A
L
A
N
S
S
D
L
L
K
E
L
Chicken
Gallus gallus
XP_419213
267
30029
S153
D
D
A
L
A
N
S
S
D
L
L
K
E
L
L
Frog
Xenopus laevis
P01212
262
29914
L149
S
D
R
D
A
A
D
L
L
R
E
L
L
A
T
Zebra Danio
Brachydanio rerio
NP_956377
234
26115
I122
E
S
D
G
T
G
A
I
S
K
K
Y
G
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
34
72.6
N.A.
82.4
82.1
N.A.
73
71.9
60.2
44.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
46.8
80.5
N.A.
91
90.3
N.A.
85.3
84.6
73.4
60.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
33.3
N.A.
86.6
86.6
N.A.
80
26.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
46.6
N.A.
93.3
93.3
N.A.
100
46.6
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
30
60
20
0
0
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
60
50
10
0
0
10
0
20
50
0
0
0
10
0
% D
% Glu:
60
0
10
0
10
0
0
10
0
10
10
0
20
50
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
10
30
0
20
0
20
0
0
0
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
10
20
50
0
0
% K
% Leu:
0
0
0
20
50
0
0
10
10
20
80
60
10
20
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
20
50
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
10
0
0
10
0
0
% R
% Ser:
10
10
0
20
0
0
20
70
70
0
0
0
0
0
0
% S
% Thr:
0
0
0
20
10
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _