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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PENK
All Species:
16.97
Human Site:
S27
Identified Species:
41.48
UniProt:
P01210
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01210
NP_001129162.1
267
30787
S27
A
T
V
R
A
E
C
S
Q
D
C
A
T
C
S
Chimpanzee
Pan troglodytes
XP_001155627
267
30741
S27
A
T
V
R
A
E
C
S
Q
D
C
A
T
C
S
Rhesus Macaque
Macaca mulatta
XP_001113720
253
27992
L23
P
S
A
T
A
D
C
L
S
R
C
S
L
C
A
Dog
Lupus familis
XP_535081
254
28765
H24
K
S
P
F
Q
T
I
H
P
P
I
L
P
A
T
Cat
Felis silvestris
Mouse
Mus musculus
P22005
268
30986
S27
A
T
V
Q
A
E
C
S
Q
D
C
A
K
C
S
Rat
Rattus norvegicus
P04094
269
30913
S27
A
T
V
Q
A
D
C
S
Q
D
C
A
K
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513911
267
29807
G27
L
A
G
R
A
G
C
G
K
D
C
A
A
C
A
Chicken
Gallus gallus
XP_419213
267
30029
G27
P
R
A
R
A
D
C
G
R
D
C
A
A
C
A
Frog
Xenopus laevis
P01212
262
29914
S27
V
E
I
R
A
D
C
S
K
D
C
A
S
C
A
Zebra Danio
Brachydanio rerio
NP_956377
234
26115
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
34
72.6
N.A.
82.4
82.1
N.A.
73
71.9
60.2
44.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
46.8
80.5
N.A.
91
90.3
N.A.
85.3
84.6
73.4
60.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
26.6
0
N.A.
86.6
80
N.A.
46.6
46.6
53.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
53.3
13.3
N.A.
93.3
93.3
N.A.
60
66.6
86.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
10
20
0
80
0
0
0
0
0
0
70
20
10
40
% A
% Cys:
0
0
0
0
0
0
80
0
0
0
80
0
0
80
0
% C
% Asp:
0
0
0
0
0
40
0
0
0
70
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
30
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
10
0
20
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
0
0
0
10
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
20
0
0
0
20
0
0
% K
% Leu:
10
0
0
0
0
0
0
10
0
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
20
0
10
0
0
0
0
0
10
10
0
0
10
0
0
% P
% Gln:
0
0
0
20
10
0
0
0
40
0
0
0
0
0
0
% Q
% Arg:
0
10
0
50
0
0
0
0
10
10
0
0
0
0
0
% R
% Ser:
0
20
0
0
0
0
0
50
10
0
0
10
10
0
40
% S
% Thr:
0
40
0
10
0
10
0
0
0
0
0
0
20
0
10
% T
% Val:
10
0
40
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _