Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LHB All Species: 20.91
Human Site: T117 Identified Species: 57.5
UniProt: P01229 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01229 NP_000885.1 141 15345 T117 C G P C R R S T S D C G G P K
Chimpanzee Pan troglodytes Q2Q1P2 141 15315 T117 C G P C R R S T S D C G G P K
Rhesus Macaque Macaca mulatta NP_001028100 165 17662 T117 C A L C R R S T S D C G G P K
Dog Lupus familis XP_533624 479 52762 N455 C G P C R L S N S D C G G P R
Cat Felis silvestris
Mouse Mus musculus O09108 141 15009 S117 C G P C R L S S S D C G G P R
Rat Rattus norvegicus P01230 141 15159 S117 C G P C R L S S S D C G G P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506129 129 14437 L101 Y Y S Y P M A L S C K C G K C
Chicken Gallus gallus
Frog Xenopus laevis NP_001079224 137 15254 Y112 C N Q C K M D Y S D C T V Q S
Zebra Danio Brachydanio rerio NP_991185 140 15516 T117 C S L C T I N T S D C T I Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 75.1 23.1 N.A. 70.9 71.6 N.A. 34.7 N.A. 37.5 41.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 76.3 25.2 N.A. 79.4 80.1 N.A. 51 N.A. 54.6 56 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 80 N.A. 80 80 N.A. 13.3 N.A. 33.3 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 86.6 N.A. 93.3 93.3 N.A. 20 N.A. 40 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 0 12 0 0 0 0 0 0 0 0 % A
% Cys: 89 0 0 89 0 0 0 0 0 12 89 12 0 0 12 % C
% Asp: 0 0 0 0 0 0 12 0 0 89 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 56 0 0 0 0 0 0 0 0 0 67 78 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 12 0 0 0 0 0 0 12 0 0 % I
% Lys: 0 0 0 0 12 0 0 0 0 0 12 0 0 12 34 % K
% Leu: 0 0 23 0 0 34 0 12 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 23 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 12 0 0 0 0 12 12 0 0 0 0 0 0 0 % N
% Pro: 0 0 56 0 12 0 0 0 0 0 0 0 0 67 0 % P
% Gln: 0 0 12 0 0 0 0 0 0 0 0 0 0 23 0 % Q
% Arg: 0 0 0 0 67 34 0 0 0 0 0 0 0 0 34 % R
% Ser: 0 12 12 0 0 0 67 23 100 0 0 0 0 0 23 % S
% Thr: 0 0 0 0 12 0 0 45 0 0 0 23 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 12 0 12 0 0 0 12 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _