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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRL
All Species:
9.09
Human Site:
S194
Identified Species:
25
UniProt:
P01236
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01236
NP_000939.1
227
25876
S194
A
D
E
E
S
R
L
S
A
Y
Y
N
L
L
H
Chimpanzee
Pan troglodytes
XP_518264
227
25749
S194
A
D
E
E
S
R
L
S
A
Y
Y
N
L
L
H
Rhesus Macaque
Macaca mulatta
P55151
227
25953
S194
A
D
E
E
S
R
L
S
A
Y
Y
N
L
L
H
Dog
Lupus familis
XP_545363
259
29663
F226
A
D
E
D
T
R
L
F
A
F
Y
N
L
L
H
Cat
Felis silvestris
Mouse
Mus musculus
P06879
226
25478
L193
V
D
E
E
S
K
I
L
S
L
R
N
T
I
R
Rat
Rattus norvegicus
P01237
226
25734
L193
V
D
E
E
S
K
D
L
A
F
Y
N
N
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513988
227
25514
F194
A
D
E
D
S
R
L
F
A
F
Y
N
L
L
H
Chicken
Gallus gallus
P14676
229
25845
F196
A
D
E
D
S
R
L
F
A
F
Y
N
L
L
H
Frog
Xenopus laevis
NP_001086486
230
26141
F197
A
D
E
N
S
R
L
F
A
F
Y
N
L
L
H
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
97.8
70.6
N.A.
60.7
62.1
N.A.
71.8
67.6
59.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
99.5
80.6
N.A.
77.5
77.9
N.A.
86.3
81.6
77.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
33.3
46.6
N.A.
80
80
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
60
66.6
N.A.
93.3
93.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
78
0
0
0
0
0
0
0
89
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
100
0
34
0
0
12
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
100
56
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
45
0
56
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
78
% H
% Ile:
0
0
0
0
0
0
12
0
0
0
0
0
0
23
0
% I
% Lys:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
78
23
0
12
0
0
78
78
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
0
0
0
100
12
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
78
0
0
0
0
12
0
0
0
23
% R
% Ser:
0
0
0
0
89
0
0
34
12
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
12
0
0
0
0
0
0
0
12
0
0
% T
% Val:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
34
89
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _