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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRL All Species: 34.24
Human Site: S61 Identified Species: 94.17
UniProt: P01236 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01236 NP_000939.1 227 25876 S61 S H Y I H N L S S E M F S E F
Chimpanzee Pan troglodytes XP_518264 227 25749 S61 S H Y I H N L S S E M F S E F
Rhesus Macaque Macaca mulatta P55151 227 25953 S61 S H Y I H N L S S E M F S E F
Dog Lupus familis XP_545363 259 29663 S93 S H Y I H N L S S E M F N E F
Cat Felis silvestris
Mouse Mus musculus P06879 226 25478 Y60 S H Y I H T L Y T D M F I E F
Rat Rattus norvegicus P01237 226 25734 Y60 S H Y I H T L Y T D M F I E F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513988 227 25514 S61 S H Y I H S L S S E M F T E F
Chicken Gallus gallus P14676 229 25845 S63 S H Y I H Y L S S E I F N E F
Frog Xenopus laevis NP_001086486 230 26141 S64 S H Y I H S L S S E M F N E F
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 97.8 70.6 N.A. 60.7 62.1 N.A. 71.8 67.6 59.5 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 99.5 80.6 N.A. 77.5 77.9 N.A. 86.3 81.6 77.8 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 66.6 66.6 N.A. 86.6 80 86.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 80 80 N.A. 100 93.3 100 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 23 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 78 0 0 0 100 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 100 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 100 0 0 100 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 100 0 0 0 0 0 0 12 0 23 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 89 0 0 0 0 % M
% Asn: 0 0 0 0 0 45 0 0 0 0 0 0 34 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 100 0 0 0 0 23 0 78 78 0 0 0 34 0 0 % S
% Thr: 0 0 0 0 0 23 0 0 23 0 0 0 12 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 100 0 0 12 0 23 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _