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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPY All Species: 12.42
Human Site: T42 Identified Species: 30.37
UniProt: P01298 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01298 NP_002713.1 95 10445 T42 V Y P G D N A T P E Q M A Q Y
Chimpanzee Pan troglodytes XP_001152868 101 11107 T48 V Y P G D N A T P E Q M A Q Y
Rhesus Macaque Macaca mulatta P33684 36 4164
Dog Lupus familis XP_548067 93 10409 D39 L E P V Y P G D D A T P E Q M
Cat Felis silvestris
Mouse Mus musculus P10601 100 11001 T42 M Y P G D Y A T P E Q M A Q Y
Rat Rattus norvegicus P06303 98 10956 T42 M Y P G D Y A T H E Q R A Q Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512214 97 11071 P41 D N P G E D A P A E D M A R Y
Chicken Gallus gallus P28673 97 11078 P41 D S P G E D A P A E D M A R Y
Frog Xenopus laevis P33689 97 11360 P41 D N P G E D A P A E D M A K Y
Zebra Danio Brachydanio rerio Q9I8P3 96 11013 P41 D N P G E D A P A E E L A K Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94 37.8 74.7 N.A. 60 60.2 N.A. 34 32.9 32.9 33.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 94 37.8 81 N.A. 65 63.2 N.A. 51.5 51.5 53.6 48.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 13.3 N.A. 86.6 73.3 N.A. 46.6 46.6 46.6 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 0 20 N.A. 93.3 80 N.A. 66.6 66.6 66.6 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 80 0 40 10 0 0 80 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 40 0 0 0 40 40 0 10 10 0 30 0 0 0 0 % D
% Glu: 0 10 0 0 40 0 0 0 0 80 10 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 80 0 0 10 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % K
% Leu: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % L
% Met: 20 0 0 0 0 0 0 0 0 0 0 60 0 0 10 % M
% Asn: 0 30 0 0 0 20 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 90 0 0 10 0 40 30 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 40 0 0 50 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 20 0 % R
% Ser: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 40 0 0 10 0 0 0 0 % T
% Val: 20 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 40 0 0 10 20 0 0 0 0 0 0 0 0 80 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _