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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPY All Species: 15.15
Human Site: Y36 Identified Species: 37.04
UniProt: P01298 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01298 NP_002713.1 95 10445 Y36 G A P L E P V Y P G D N A T P
Chimpanzee Pan troglodytes XP_001152868 101 11107 Y42 G A P L E P V Y P G D N A T P
Rhesus Macaque Macaca mulatta P33684 36 4164
Dog Lupus familis XP_548067 93 10409 E33 G T R G A P L E P V Y P G D D
Cat Felis silvestris
Mouse Mus musculus P10601 100 11001 Y36 G A P L E P M Y P G D Y A T P
Rat Rattus norvegicus P06303 98 10956 Y36 G A P L E P M Y P G D Y A T H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512214 97 11071 N35 A Y P S K P D N P G E D A P A
Chicken Gallus gallus P28673 97 11078 S35 A Y P S K P D S P G E D A P A
Frog Xenopus laevis P33689 97 11360 N35 A Y P S K P D N P G E D A P A
Zebra Danio Brachydanio rerio Q9I8P3 96 11013 N35 G Y P T K P D N P G E D A P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94 37.8 74.7 N.A. 60 60.2 N.A. 34 32.9 32.9 33.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 94 37.8 81 N.A. 65 63.2 N.A. 51.5 51.5 53.6 48.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 20 N.A. 86.6 80 N.A. 33.3 33.3 33.3 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 0 26.6 N.A. 93.3 86.6 N.A. 53.3 53.3 53.3 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 30 40 0 0 10 0 0 0 0 0 0 0 80 0 40 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 40 0 0 0 40 40 0 10 10 % D
% Glu: 0 0 0 0 40 0 0 10 0 0 40 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 60 0 0 10 0 0 0 0 0 80 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 40 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 40 0 0 10 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 30 0 0 0 20 0 0 0 % N
% Pro: 0 0 80 0 0 90 0 0 90 0 0 10 0 40 30 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 30 0 0 0 10 0 0 0 0 0 0 0 % S
% Thr: 0 10 0 10 0 0 0 0 0 0 0 0 0 40 0 % T
% Val: 0 0 0 0 0 0 20 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 40 0 0 0 0 0 40 0 0 10 20 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _