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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INS
All Species:
4.55
Human Site:
S85
Identified Species:
14.29
UniProt:
P01308
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01308
NP_000198.1
110
11981
S85
Q
P
L
A
L
E
G
S
L
Q
K
R
G
I
V
Chimpanzee
Pan troglodytes
P30410
110
12006
S85
Q
P
L
A
L
E
G
S
L
Q
K
R
G
I
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_863200
194
21311
E160
R
M
L
A
K
E
L
E
A
F
R
E
A
K
R
Cat
Felis silvestris
Mouse
Mus musculus
P01326
110
12346
A85
Q
T
L
A
L
E
V
A
Q
Q
K
R
G
I
V
Rat
Rattus norvegicus
P01322
110
12402
A85
Q
T
L
A
L
E
V
A
R
Q
K
R
G
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P67970
107
11962
E82
P
F
Q
Q
E
E
Y
E
K
V
K
R
G
I
V
Frog
Xenopus laevis
P12707
106
12189
Q81
Q
F
Q
P
Q
E
Y
Q
K
M
K
R
G
I
V
Zebra Danio
Brachydanio rerio
O73727
108
11885
L83
A
F
K
D
H
A
E
L
I
R
K
R
G
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
N.A.
21.6
N.A.
81.8
82.7
N.A.
N.A.
62.7
56.3
45.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
N.A.
33.5
N.A.
85.4
86.3
N.A.
N.A.
69
66.3
57.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
20
N.A.
73.3
73.3
N.A.
N.A.
40
46.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
33.3
N.A.
80
80
N.A.
N.A.
40
46.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
63
0
13
0
25
13
0
0
0
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
13
88
13
25
0
0
0
13
0
0
0
% E
% Phe:
0
38
0
0
0
0
0
0
0
13
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
25
0
0
0
0
0
88
0
0
% G
% His:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
13
0
0
0
0
88
0
% I
% Lys:
0
0
13
0
13
0
0
0
25
0
88
0
0
13
0
% K
% Leu:
0
0
63
0
50
0
13
13
25
0
0
0
0
0
0
% L
% Met:
0
13
0
0
0
0
0
0
0
13
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
13
25
0
13
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
63
0
25
13
13
0
0
13
13
50
0
0
0
0
0
% Q
% Arg:
13
0
0
0
0
0
0
0
13
13
13
88
0
0
13
% R
% Ser:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% S
% Thr:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
25
0
0
13
0
0
0
0
88
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _