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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGF2
All Species:
20.91
Human Site:
S95
Identified Species:
51.11
UniProt:
P01344
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01344
NP_000603.1
180
20140
S95
A
K
S
E
R
D
V
S
T
P
P
T
V
L
P
Chimpanzee
Pan troglodytes
XP_001153640
240
26753
S151
S
A
F
P
R
R
E
S
R
H
L
L
T
S
P
Rhesus Macaque
Macaca mulatta
XP_001093911
208
23233
K116
C
A
P
L
K
P
A
K
S
A
R
S
V
R
A
Dog
Lupus familis
XP_540785
184
20438
S98
A
K
S
E
R
D
V
S
T
P
P
T
V
L
P
Cat
Felis silvestris
Mouse
Mus musculus
P09535
180
20012
S95
A
K
S
E
R
D
V
S
T
S
Q
A
V
L
P
Rat
Rattus norvegicus
P01346
180
20068
S95
A
K
S
E
R
D
V
S
T
S
Q
A
V
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507349
242
27362
K116
C
A
P
I
K
P
A
K
S
A
R
S
V
R
A
Chicken
Gallus gallus
P33717
187
20818
S95
V
K
S
E
R
D
L
S
A
T
S
L
A
G
L
Frog
Xenopus laevis
Q6INW9
217
25059
S127
S
K
N
E
R
D
V
S
T
A
P
A
T
A
I
Zebra Danio
Brachydanio rerio
NP_001001815
212
24354
S119
A
K
S
E
R
D
V
S
A
T
S
L
Q
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60
33.1
90.2
N.A.
83.8
85
N.A.
33.8
55
46.5
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
63.7
46.1
93.4
N.A.
89.4
91.1
N.A.
45
68.9
58
59.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
6.6
100
N.A.
80
80
N.A.
6.6
40
53.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
26.6
100
N.A.
80
80
N.A.
26.6
46.6
66.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
30
0
0
0
0
20
0
20
30
0
30
10
10
20
% A
% Cys:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
70
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
20
% I
% Lys:
0
70
0
0
20
0
0
20
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
10
0
0
0
10
30
0
40
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
20
10
0
20
0
0
0
20
30
0
0
0
50
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
20
0
10
0
0
% Q
% Arg:
0
0
0
0
80
10
0
0
10
0
20
0
0
20
0
% R
% Ser:
20
0
60
0
0
0
0
80
20
20
20
20
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
50
20
0
20
20
0
0
% T
% Val:
10
0
0
0
0
0
60
0
0
0
0
0
60
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _