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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LTA All Species: 17.58
Human Site: S121 Identified Species: 38.67
UniProt: P01374 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01374 NP_000586.2 205 22297 S121 V F S G K A Y S P K A T S S P
Chimpanzee Pan troglodytes P61125 205 22331 S121 V F S G K A Y S P K A T S S P
Rhesus Macaque Macaca mulatta Q5TM20 205 22341 S121 V F S G K A Y S P K A T P T P
Dog Lupus familis XP_848886 233 25475 F149 V F S G E G C F P K A T P T P
Cat Felis silvestris
Mouse Mus musculus P09225 202 21980 S118 V F S G E S C S P R A I P T P
Rat Rattus norvegicus Q06332 202 22093 S118 V F S G E S C S P R A I P T P
Wallaby Macropus eugenll Q9XT48 201 21518 C117 V V F S G A S C S E I T P T L
Platypus Ornith. anatinus XP_001515935 137 15111 P52 L F K D S S C P A N P D D S P
Chicken Gallus gallus
Frog Xenopus laevis NP_001108250 225 25393 T133 K G F Y F V Y T Q V S F T G P
Zebra Danio Brachydanio rerio NP_001019618 242 26747 E157 S Y E T L C V E D V E G D G Q
Tiger Blowfish Takifugu rubipres NP_001033074 250 27690 I166 H S P G K S H I P L S H R V W
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97.5 67.3 N.A. 72.1 72.6 57 26.3 N.A. 27.1 28.9 27.2 N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 98 74.2 N.A. 80.9 81.4 69.2 37.5 N.A. 40.8 43.3 43.6 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 60 N.A. 53.3 53.3 20 20 N.A. 13.3 0 20 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 73.3 N.A. 80 80 33.3 33.3 N.A. 33.3 6.6 40 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 37 0 0 10 0 55 0 0 0 0 % A
% Cys: 0 0 0 0 0 10 37 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 10 0 0 10 19 0 0 % D
% Glu: 0 0 10 0 28 0 0 10 0 10 10 0 0 0 0 % E
% Phe: 0 64 19 0 10 0 0 10 0 0 0 10 0 0 0 % F
% Gly: 0 10 0 64 10 10 0 0 0 0 0 10 0 19 0 % G
% His: 10 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 10 19 0 0 0 % I
% Lys: 10 0 10 0 37 0 0 0 0 37 0 0 0 0 0 % K
% Leu: 10 0 0 0 10 0 0 0 0 10 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 0 10 64 0 10 0 46 0 73 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 19 0 0 10 0 0 % R
% Ser: 10 10 55 10 10 37 10 46 10 0 19 0 19 28 0 % S
% Thr: 0 0 0 10 0 0 0 10 0 0 0 46 10 46 0 % T
% Val: 64 10 0 0 0 10 10 0 0 19 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 10 0 10 0 0 37 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _