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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LTA
All Species:
28.18
Human Site:
S140
Identified Species:
62
UniProt:
P01374
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01374
NP_000586.2
205
22297
S140
H
E
V
Q
L
F
S
S
Q
Y
P
F
H
V
P
Chimpanzee
Pan troglodytes
P61125
205
22331
S140
H
E
V
Q
L
F
S
S
Q
Y
P
F
H
V
P
Rhesus Macaque
Macaca mulatta
Q5TM20
205
22341
S140
H
E
V
Q
L
F
S
S
Q
Y
P
F
H
V
P
Dog
Lupus familis
XP_848886
233
25475
S168
H
E
V
Q
L
F
S
S
Q
Y
P
F
H
V
P
Cat
Felis silvestris
Mouse
Mus musculus
P09225
202
21980
S137
H
E
V
Q
L
F
S
S
Q
Y
P
F
H
V
P
Rat
Rattus norvegicus
Q06332
202
22093
S137
H
E
V
Q
L
F
S
S
Q
Y
P
F
H
V
P
Wallaby
Macropus eugenll
Q9XT48
201
21518
S136
H
E
V
L
L
F
S
S
K
Y
Q
V
H
V
P
Platypus
Ornith. anatinus
XP_001515935
137
15111
S71
N
V
S
R
F
S
D
S
Y
E
Y
E
V
S
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001108250
225
25393
T152
E
P
L
H
L
T
H
T
V
N
V
V
R
E
S
Zebra Danio
Brachydanio rerio
NP_001019618
242
26747
D176
H
T
I
N
R
Y
T
D
A
V
R
E
K
M
P
Tiger Blowfish
Takifugu rubipres
NP_001033074
250
27690
L185
S
I
G
T
E
T
T
L
L
N
A
V
R
S
A
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.5
67.3
N.A.
72.1
72.6
57
26.3
N.A.
27.1
28.9
27.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98
74.2
N.A.
80.9
81.4
69.2
37.5
N.A.
40.8
43.3
43.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
73.3
6.6
N.A.
6.6
13.3
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
80
20
N.A.
20
40
6.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% D
% Glu:
10
64
0
0
10
0
0
0
0
10
0
19
0
10
0
% E
% Phe:
0
0
0
0
10
64
0
0
0
0
0
55
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
73
0
0
10
0
0
10
0
0
0
0
0
64
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% K
% Leu:
0
0
10
10
73
0
0
10
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
10
0
0
10
0
0
0
0
0
19
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
55
0
0
0
73
% P
% Gln:
0
0
0
55
0
0
0
0
55
0
10
0
0
0
0
% Q
% Arg:
0
0
0
10
10
0
0
0
0
0
10
0
19
0
0
% R
% Ser:
10
0
10
0
0
10
64
73
0
0
0
0
0
19
10
% S
% Thr:
0
10
0
10
0
19
19
10
0
0
0
0
0
0
0
% T
% Val:
0
10
64
0
0
0
0
0
10
10
10
28
10
64
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
10
64
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _