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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL1B
All Species:
6.36
Human Site:
T84
Identified Species:
20
UniProt:
P01584
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01584
NP_000567.1
269
30748
T84
M
L
V
P
C
P
Q
T
F
Q
E
N
D
L
S
Chimpanzee
Pan troglodytes
XP_001146864
286
32552
T101
M
L
V
P
C
P
Q
T
F
Q
E
N
D
L
S
Rhesus Macaque
Macaca mulatta
P48090
269
30462
I84
M
L
V
P
C
P
Q
I
F
Q
D
N
D
L
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P10749
269
30913
Q85
V
S
F
P
W
T
F
Q
D
E
D
M
S
T
F
Rat
Rattus norvegicus
Q63264
268
30625
F84
P
M
S
C
P
W
S
F
Q
D
E
D
P
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521209
339
37940
S147
Q
A
V
S
Y
N
T
S
F
M
D
R
D
L
M
Chicken
Gallus gallus
NP_989855
267
29804
D77
L
R
R
P
R
S
R
D
F
A
D
S
D
L
S
Frog
Xenopus laevis
NP_001079074
283
31711
G87
R
G
K
E
R
F
F
G
D
E
D
L
L
G
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.3
90.3
N.A.
N.A.
68.4
67.2
N.A.
37.1
30.1
35.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.7
95.1
N.A.
N.A.
79.9
79.5
N.A.
51
49.8
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
N.A.
N.A.
6.6
6.6
N.A.
26.6
33.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
N.A.
N.A.
26.6
26.6
N.A.
40
60
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
0
0
0
0
0
13
0
0
0
0
0
% A
% Cys:
0
0
0
13
38
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
13
25
13
63
13
63
0
0
% D
% Glu:
0
0
0
13
0
0
0
0
0
25
38
0
0
0
0
% E
% Phe:
0
0
13
0
0
13
25
13
63
0
0
0
0
0
13
% F
% Gly:
0
13
0
0
0
0
0
13
0
0
0
0
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
13
38
0
0
0
0
0
0
0
0
0
13
13
63
13
% L
% Met:
38
13
0
0
0
0
0
0
0
13
0
13
0
0
13
% M
% Asn:
0
0
0
0
0
13
0
0
0
0
0
38
0
0
0
% N
% Pro:
13
0
0
63
13
38
0
0
0
0
0
0
13
0
0
% P
% Gln:
13
0
0
0
0
0
38
13
13
38
0
0
0
0
0
% Q
% Arg:
13
13
13
0
25
0
13
0
0
0
0
13
0
0
0
% R
% Ser:
0
13
13
13
0
13
13
13
0
0
0
13
13
13
50
% S
% Thr:
0
0
0
0
0
13
13
25
0
0
0
0
0
13
13
% T
% Val:
13
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
13
13
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _