Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPO All Species: 8.79
Human Site: S173 Identified Species: 32.22
UniProt: P01588 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01588 NP_000790.2 193 21307 S173 R K L F R V Y S N F L R G K L
Chimpanzee Pan troglodytes XP_519268 193 21387 S173 R K L F R V Y S N F L R G K L
Rhesus Macaque Macaca mulatta Q28513 192 21063 N173 K L F R V Y S N F L R G K L K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P07321 192 21347 A172 C K L F R V Y A N F L R G K L
Rat Rattus norvegicus P29676 192 21267 S172 C K L F R V Y S N F L R G K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q2XNF5 183 20366 F163 L F Q V H V N F L R G K A R L
Tiger Blowfish Takifugu rubipres Q6JV22 185 20530 L166 L Q V H I N F L R G K V R L I
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 90.6 N.A. N.A. 78.7 80.8 N.A. N.A. N.A. N.A. 37.3 33.6 N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 95.8 N.A. N.A. 86.5 88 N.A. N.A. N.A. N.A. 55.9 50.2 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 N.A. N.A. 86.6 93.3 N.A. N.A. N.A. N.A. 13.3 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 N.A. N.A. 93.3 93.3 N.A. N.A. N.A. N.A. 26.6 26.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 15 0 0 0 0 15 0 0 % A
% Cys: 29 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 15 15 58 0 0 15 15 15 58 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 15 15 15 58 0 0 % G
% His: 0 0 0 15 15 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 15 % I
% Lys: 15 58 0 0 0 0 0 0 0 0 15 15 15 58 15 % K
% Leu: 29 15 58 0 0 0 0 15 15 15 58 0 0 29 72 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 15 15 15 58 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 15 15 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 29 0 0 15 58 0 0 0 15 15 15 58 15 15 0 % R
% Ser: 0 0 0 0 0 0 15 43 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 15 15 15 72 0 0 0 0 0 15 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 15 58 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _