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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 11.21
Human Site: T74 Identified Species: 61.67
UniProt: P01599 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01599 XP_002342271 108 11814 T74 A G T E F T L T I S S L Q P E
Chimpanzee Pan troglodytes XP_001141313 236 25781 T96 S G T E F T L T I S S L Q P D
Rhesus Macaque Macaca mulatta XP_001114402 125 13596 S75 L L I Y A A S S L Q S G V P S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P01652 108 11792 T74 Y G T D F T L T I S S L E D E
Rat Rattus norvegicus XP_002726185 108 11704 S74 V P S R F S G S G S G T D Y S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.7 68 N.A. N.A. 70.3 69.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 41.5 72 N.A. N.A. 82.4 77.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 86.6 13.3 N.A. N.A. 73.3 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 N.A. N.A. 86.6 33.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 0 20 20 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 20 0 0 0 0 0 0 0 0 20 20 20 % D
% Glu: 0 0 0 40 0 0 0 0 0 0 0 0 20 0 40 % E
% Phe: 0 0 0 0 80 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 60 0 0 0 0 20 0 20 0 20 20 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 20 0 0 0 0 0 60 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 20 20 0 0 0 0 60 0 20 0 0 60 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 20 0 0 0 0 0 0 0 0 0 0 0 60 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 20 0 0 40 0 0 % Q
% Arg: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 20 0 20 0 0 20 20 40 0 80 80 0 0 0 40 % S
% Thr: 0 0 60 0 0 60 0 60 0 0 0 20 0 0 0 % T
% Val: 20 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 20 0 0 20 0 0 0 0 0 0 0 0 0 20 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _