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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 13.64
Human Site: Y88 Identified Species: 60
UniProt: P01623 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01623 XP_002347049 109 11746 Y88 P E D F A V Y Y C Q Q Y G S L
Chimpanzee Pan troglodytes XP_001141313 236 25781 Y109 P D D F A T Y Y C Q Q F G S L
Rhesus Macaque Macaca mulatta XP_001089800 235 25361 Y107 P E D F A A Y Y C L Q D G T S
Dog Lupus familis XP_854722 117 12765 S96 T D F S F T I S S L E P E D V
Cat Felis silvestris
Mouse Mus musculus P01670 111 12021 Y91 E E D A A T Y Y C Q H S R E L
Rat Rattus norvegicus XP_002726463 237 26054 Y110 A D D I A T Y Y C Q Q K L P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32.6 40 64 N.A. 66.6 32 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 40.2 42.9 73.5 N.A. 79.2 38.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 80 66.6 0 N.A. 53.3 53.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 73.3 20 N.A. 53.3 60 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 17 84 17 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 84 0 0 0 0 0 0 % C
% Asp: 0 50 84 0 0 0 0 0 0 0 0 17 0 17 0 % D
% Glu: 17 50 0 0 0 0 0 0 0 0 17 0 17 17 0 % E
% Phe: 0 0 17 50 17 0 0 0 0 0 0 17 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % H
% Ile: 0 0 0 17 0 0 17 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 34 0 0 17 0 67 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 50 0 0 0 0 0 0 0 0 0 0 17 0 17 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 67 67 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % R
% Ser: 0 0 0 17 0 0 0 17 17 0 0 17 0 34 17 % S
% Thr: 17 0 0 0 0 67 0 0 0 0 0 0 0 17 0 % T
% Val: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 84 84 0 0 0 17 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _