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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 1.52
Human Site: T49 Identified Species: 5.56
UniProt: P01718 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01718 XP_002345514 106 11278 T49 P L L V I Y H T S E R P S E I
Chimpanzee Pan troglodytes XP_001161517 144 15546 D74 P V L V I Y S D S N R P S G I
Rhesus Macaque Macaca mulatta XP_001114758 359 37268 D285 P V L V I Y A D S E R P S G I
Dog Lupus familis XP_856357 232 25027 D69 P L L I I Y N D N S Q P S G I
Cat Felis silvestris
Mouse Mus musculus P03977 111 12024 A55 P K L L I Y A A S N Q G S G V
Rat Rattus norvegicus XP_002724802 116 12597 Y53 P K K Y A Q W Y Q Q K P D Q S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P04210 113 11676 K54 Y Y G W Y Q Q K A P G S A P V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.7 20.3 30.6 N.A. 44.1 50 N.A. N.A. 37.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 53.4 23.6 39.2 N.A. 60.3 60.3 N.A. N.A. 58.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 66.6 73.3 53.3 N.A. 40 13.3 N.A. N.A. 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 73.3 80 80 N.A. 60 33.3 N.A. N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 15 0 29 15 15 0 0 0 15 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 43 0 0 0 0 15 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 29 0 0 0 15 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 15 0 0 0 0 0 0 0 15 15 0 58 0 % G
% His: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 15 72 0 0 0 0 0 0 0 0 0 58 % I
% Lys: 0 29 15 0 0 0 0 15 0 0 15 0 0 0 0 % K
% Leu: 0 29 72 15 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 15 0 15 29 0 0 0 0 0 % N
% Pro: 86 0 0 0 0 0 0 0 0 15 0 72 0 15 0 % P
% Gln: 0 0 0 0 0 29 15 0 15 15 29 0 0 15 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 43 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 15 0 58 15 0 15 72 0 15 % S
% Thr: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % T
% Val: 0 29 0 43 0 0 0 0 0 0 0 0 0 0 29 % V
% Trp: 0 0 0 15 0 0 15 0 0 0 0 0 0 0 0 % W
% Tyr: 15 15 0 15 15 72 0 15 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _