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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD4
All Species:
8.18
Human Site:
S67
Identified Species:
30
UniProt:
P01730
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01730
NP_000607.1
458
51111
S67
K
I
L
G
N
Q
G
S
F
L
T
K
G
P
S
Chimpanzee
Pan troglodytes
P16004
458
51039
S67
K
I
L
G
N
Q
G
S
F
L
T
K
G
P
S
Rhesus Macaque
Macaca mulatta
P16003
458
50866
L67
K
I
L
G
I
Q
G
L
F
L
T
K
G
P
S
Dog
Lupus familis
XP_855581
463
51636
S67
Q
I
L
G
N
Q
G
S
F
W
T
V
G
S
S
Cat
Felis silvestris
Mouse
Mus musculus
P06332
457
51278
K68
K
I
L
G
Q
H
G
K
G
V
L
I
R
G
G
Rat
Rattus norvegicus
P05540
457
51419
K69
T
I
L
G
Y
K
N
K
L
L
I
K
G
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989980
487
54966
D52
K
A
I
N
N
Q
K
D
G
T
C
T
W
K
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
91.9
59.8
N.A.
55.9
54.7
N.A.
N.A.
25.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
95.6
74.3
N.A.
70.9
69.6
N.A.
N.A.
44.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
73.3
N.A.
33.3
40
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
80
N.A.
40
46.6
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
58
0
0
0
0
0
0
% F
% Gly:
0
0
0
86
0
0
72
0
29
0
0
0
72
15
15
% G
% His:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
86
15
0
15
0
0
0
0
0
15
15
0
0
0
% I
% Lys:
72
0
0
0
0
15
15
29
0
0
0
58
0
15
0
% K
% Leu:
0
0
86
0
0
0
0
15
15
58
15
0
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
15
58
0
15
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
43
0
% P
% Gln:
15
0
0
0
15
72
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% R
% Ser:
0
0
0
0
0
0
0
43
0
0
0
0
0
29
58
% S
% Thr:
15
0
0
0
0
0
0
0
0
15
58
15
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
15
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
15
0
0
15
0
0
% W
% Tyr:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _