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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 5.76
Human Site: Y52 Identified Species: 31.67
UniProt: P01776 Number Species: 4
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01776 XP_002347522 117 13091 Y52 L E W V A W K Y Q E A S N S H
Chimpanzee Pan troglodytes XP_001149684 238 26110 I70 G L E W V S L I Y S G D S T Y
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848501 162 17845 Y83 L Q W V A W I Y D S G S S T S
Cat Felis silvestris
Mouse Mus musculus P01783 136 15053 S68 L E W V A Y I S S G S S T L H
Rat Rattus norvegicus XP_002729732 155 17748 K69 V Q P G S S L K L S C V A S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 36.1 N.A. 47.5 N.A. 52.9 42.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 42 N.A. 56.7 N.A. 68.3 56.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 N.A. 46.6 N.A. 46.6 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 N.A. 66.6 N.A. 60 26.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 60 0 0 0 0 0 20 0 20 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 20 0 0 20 0 0 0 % D
% Glu: 0 40 20 0 0 0 0 0 0 20 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 20 0 0 20 0 0 0 0 0 20 40 0 0 0 20 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 40 % H
% Ile: 0 0 0 0 0 0 40 20 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 20 20 0 0 0 0 0 0 0 % K
% Leu: 60 20 0 0 0 0 40 0 20 0 0 0 0 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % N
% Pro: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 40 0 0 0 0 0 0 20 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 20 40 0 20 20 60 20 60 40 40 20 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 20 40 0 % T
% Val: 20 0 0 60 20 0 0 0 0 0 0 20 0 0 0 % V
% Trp: 0 0 60 20 0 40 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 20 0 40 20 0 0 0 0 0 20 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _