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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGR All Species: 13.94
Human Site: T718 Identified Species: 43.81
UniProt: P01833 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01833 NP_002635.2 764 83284 T718 G K E E F V A T T E S T T E T
Chimpanzee Pan troglodytes XP_514153 873 95182 T827 G K D E F V A T T E S T T E T
Rhesus Macaque Macaca mulatta XP_001083307 803 88907 T757 K N V E F V A T P E S T T E T
Dog Lupus familis XP_537133 780 85095 A713 G H D E C S A A T T T T E K T
Cat Felis silvestris
Mouse Mus musculus O70570 771 84980 T725 G K D E I V T T T E C T A E P
Rat Rattus norvegicus P15083 769 84780 T723 G K D E I E T T T E C T T E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508652 755 82243 K709 E E E F I P S K E N P E V V E
Chicken Gallus gallus NP_001038109 648 70552 G607 E T K K A K R G S K E D A D L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.6 72.2 67.8 N.A. 64.9 63.8 N.A. 50.1 37.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 86.3 76.5 80.6 N.A. 78.2 78.2 N.A. 65.4 53.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 73.3 40 N.A. 60 60 N.A. 6.6 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 73.3 60 N.A. 66.6 66.6 N.A. 20 33.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 13 0 50 13 0 0 0 0 25 0 0 % A
% Cys: 0 0 0 0 13 0 0 0 0 0 25 0 0 0 0 % C
% Asp: 0 0 50 0 0 0 0 0 0 0 0 13 0 13 0 % D
% Glu: 25 13 25 75 0 13 0 0 13 63 13 13 13 63 13 % E
% Phe: 0 0 0 13 38 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 63 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % G
% His: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 38 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 13 50 13 13 0 13 0 13 0 13 0 0 0 13 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 13 0 0 0 0 0 0 0 13 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 13 0 0 13 0 13 0 0 0 25 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 13 13 0 13 0 38 0 0 0 0 % S
% Thr: 0 13 0 0 0 0 25 63 63 13 13 75 50 0 50 % T
% Val: 0 0 13 0 0 50 0 0 0 0 0 0 13 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _