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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IGHE All Species: 9.7
Human Site: S120 Identified Species: 30.48
UniProt: P01854 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01854 XP_002347518 428 47019 S120 T V K I L Q S S C D G G G H F
Chimpanzee Pan troglodytes XP_522970 288 32022
Rhesus Macaque Macaca mulatta XP_001116734 465 50902 S157 T V K I L Q S S C D D D G H F
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P06336 421 47302 Y120 F H S T I Q L Y C F I Y G H I
Rat Rattus norvegicus P01855 429 48653 F126 S T I Q L Y C F V Y G H I Q N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507959 649 72041 S267 T V K L L H S S C D P R G D S
Chicken Gallus gallus P01875 446 48155 S120 F V T M H P P S R E D F E G P
Frog Xenopus laevis NP_001083154 562 62536 L258 I K P T V E I L Q G P C A S S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 23.3 78 N.A. N.A. 44.3 46.1 N.A. 31.1 26.6 25.7 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 40.8 81.9 N.A. N.A. 61.9 62.4 N.A. 44.8 44.8 40.7 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 86.6 N.A. N.A. 26.6 13.3 N.A. 60 13.3 0 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 86.6 N.A. N.A. 33.3 20 N.A. 66.6 26.6 13.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % A
% Cys: 0 0 0 0 0 0 13 0 50 0 0 13 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 38 25 13 0 13 0 % D
% Glu: 0 0 0 0 0 13 0 0 0 13 0 0 13 0 0 % E
% Phe: 25 0 0 0 0 0 0 13 0 13 0 13 0 0 25 % F
% Gly: 0 0 0 0 0 0 0 0 0 13 25 13 50 13 0 % G
% His: 0 13 0 0 13 13 0 0 0 0 0 13 0 38 0 % H
% Ile: 13 0 13 25 13 0 13 0 0 0 13 0 13 0 13 % I
% Lys: 0 13 38 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 13 50 0 13 13 0 0 0 0 0 0 0 % L
% Met: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % N
% Pro: 0 0 13 0 0 13 13 0 0 0 25 0 0 0 13 % P
% Gln: 0 0 0 13 0 38 0 0 13 0 0 0 0 13 0 % Q
% Arg: 0 0 0 0 0 0 0 0 13 0 0 13 0 0 0 % R
% Ser: 13 0 13 0 0 0 38 50 0 0 0 0 0 13 25 % S
% Thr: 38 13 13 25 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 50 0 0 13 0 0 0 13 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 13 0 13 0 13 0 13 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _