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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGHG1
All Species:
6.36
Human Site:
S137
Identified Species:
17.5
UniProt:
P01857
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01857
XP_002348298
330
36106
S137
P
K
D
T
L
M
I
S
R
T
P
E
V
T
C
Chimpanzee
Pan troglodytes
XP_001168435
401
43934
I173
P
E
P
K
S
C
D
I
P
P
P
C
P
R
C
Rhesus Macaque
Macaca mulatta
XP_001100439
438
47752
S176
P
K
D
T
L
M
I
S
R
T
P
E
V
T
C
Dog
Lupus familis
XP_856442
233
24837
C41
G
Q
T
A
S
I
T
C
R
G
N
S
I
G
R
Cat
Felis silvestris
Mouse
Mus musculus
P03987
398
43911
S180
P
R
E
A
Q
Y
N
S
T
F
R
V
V
S
A
Rat
Rattus norvegicus
P20759
326
35927
L134
K
D
V
L
T
I
T
L
T
P
K
V
T
C
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507984
588
64292
C328
A
G
T
P
K
V
T
C
V
V
V
D
L
G
F
Chicken
Gallus gallus
P01875
446
48155
K231
F
V
D
I
F
I
S
K
S
A
T
L
T
C
R
Frog
Xenopus laevis
NP_001083154
562
62536
V370
P
S
P
K
D
L
L
V
T
K
E
A
K
V
Y
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.8
68.9
20.9
N.A.
53
63.3
N.A.
26.7
24.2
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
75.3
72.1
37.8
N.A.
64.8
79
N.A.
35.8
38.7
37.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
100
6.6
N.A.
20
0
N.A.
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
26.6
N.A.
40
6.6
N.A.
20
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
23
0
0
0
0
0
12
0
12
0
0
12
% A
% Cys:
0
0
0
0
0
12
0
23
0
0
0
12
0
23
34
% C
% Asp:
0
12
34
0
12
0
12
0
0
0
0
12
0
0
0
% D
% Glu:
0
12
12
0
0
0
0
0
0
0
12
23
0
0
0
% E
% Phe:
12
0
0
0
12
0
0
0
0
12
0
0
0
0
12
% F
% Gly:
12
12
0
0
0
0
0
0
0
12
0
0
0
23
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
0
34
23
12
0
0
0
0
12
0
0
% I
% Lys:
12
23
0
23
12
0
0
12
0
12
12
0
12
0
0
% K
% Leu:
0
0
0
12
23
12
12
12
0
0
0
12
12
0
0
% L
% Met:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
12
0
0
0
0
% N
% Pro:
56
0
23
12
0
0
0
0
12
23
34
0
12
0
0
% P
% Gln:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
0
0
0
0
0
0
34
0
12
0
0
12
23
% R
% Ser:
0
12
0
0
23
0
12
34
12
0
0
12
0
12
0
% S
% Thr:
0
0
23
23
12
0
34
0
34
23
12
0
23
23
0
% T
% Val:
0
12
12
0
0
12
0
12
12
12
12
23
34
12
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _