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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IGHG1 All Species: 8.48
Human Site: T182 Identified Species: 23.33
UniProt: P01857 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01857 XP_002348298 330 36106 T182 R E E Q Y N S T Y R V V S V L
Chimpanzee Pan troglodytes XP_001168435 401 43934 M218 P K P K D T L M I T R T P E V
Rhesus Macaque Macaca mulatta XP_001100439 438 47752 T221 R E T Q Y N S T Y R V V S V L
Dog Lupus familis XP_856442 233 24837 G86 R F S G T N S G S T A T L T I
Cat Felis silvestris
Mouse Mus musculus P03987 398 43911 A225 I S K P K G R A Q T P Q V Y T
Rat Rattus norvegicus P20759 326 35927 F179 E E Q F N S T F R S V S E L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507984 588 64292 F373 Q R N G T Y R F V S E R D V S
Chicken Gallus gallus P01875 446 48155 T276 L Q S N G L Y T V D G V A T V
Frog Xenopus laevis NP_001083154 562 62536 T415 P E K A Y D G T F T V K S T L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.8 68.9 20.9 N.A. 53 63.3 N.A. 26.7 24.2 26.6 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 75.3 72.1 37.8 N.A. 64.8 79 N.A. 35.8 38.7 37.5 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 93.3 20 N.A. 0 13.3 N.A. 6.6 13.3 40 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 93.3 26.6 N.A. 6.6 40 N.A. 13.3 33.3 60 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 0 0 0 12 0 0 12 0 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 12 12 0 0 0 12 0 0 12 0 0 % D
% Glu: 12 45 12 0 0 0 0 0 0 0 12 0 12 12 0 % E
% Phe: 0 12 0 12 0 0 0 23 12 0 0 0 0 0 0 % F
% Gly: 0 0 0 23 12 12 12 12 0 0 12 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 0 0 0 0 0 0 12 0 0 0 0 0 12 % I
% Lys: 0 12 23 12 12 0 0 0 0 0 0 12 0 0 0 % K
% Leu: 12 0 0 0 0 12 12 0 0 0 0 0 12 12 34 % L
% Met: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % M
% Asn: 0 0 12 12 12 34 0 0 0 0 0 0 0 0 0 % N
% Pro: 23 0 12 12 0 0 0 0 0 0 12 0 12 0 12 % P
% Gln: 12 12 12 23 0 0 0 0 12 0 0 12 0 0 0 % Q
% Arg: 34 12 0 0 0 0 23 0 12 23 12 12 0 0 0 % R
% Ser: 0 12 23 0 0 12 34 0 12 23 0 12 34 0 12 % S
% Thr: 0 0 12 0 23 12 12 45 0 45 0 23 0 34 12 % T
% Val: 0 0 0 0 0 0 0 0 23 0 45 34 12 34 23 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 34 12 12 0 23 0 0 0 0 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _