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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGHG2
All Species:
12.42
Human Site:
S74
Identified Species:
34.17
UniProt:
P01859
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01859
XP_002348298
326
35901
S74
S
V
V
T
V
P
S
S
N
F
G
T
Q
T
Y
Chimpanzee
Pan troglodytes
XP_001168435
401
43934
S110
S
V
L
T
V
P
S
S
T
F
G
T
Q
T
Y
Rhesus Macaque
Macaca mulatta
XP_001099592
413
44999
S112
S
V
V
T
V
P
S
S
S
L
G
T
Q
T
Y
Dog
Lupus familis
XP_856442
233
24837
Cat
Felis silvestris
Mouse
Mus musculus
P01868
324
35686
P74
S
V
T
V
P
S
S
P
R
P
S
E
T
V
T
Rat
Rattus norvegicus
P20759
326
35927
T74
S
V
T
V
P
S
S
T
W
P
S
Q
T
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507984
588
64292
E265
S
Q
I
T
L
P
T
E
K
W
R
S
E
S
V
Chicken
Gallus gallus
P01875
446
48155
E76
R
I
Q
M
N
Q
S
E
G
K
E
K
Q
P
F
Frog
Xenopus laevis
NP_001083154
562
62536
S215
S
Q
L
T
I
P
L
S
D
W
K
A
K
K
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71
70.6
21.1
N.A.
64.1
65.3
N.A.
27.5
25.1
25.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
74.5
74
37.1
N.A.
79.7
79.7
N.A.
36.7
39.4
37
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
86.6
0
N.A.
20
20
N.A.
20
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
0
N.A.
20
26.6
N.A.
66.6
26.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
23
0
0
12
12
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
23
0
0
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
0
12
0
34
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
12
0
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
12
12
12
12
12
12
0
% K
% Leu:
0
0
23
0
12
0
12
0
0
12
0
0
0
0
0
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
23
56
0
12
0
23
0
0
0
12
0
% P
% Gln:
0
23
12
0
0
12
0
0
0
0
0
12
45
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% R
% Ser:
78
0
0
0
0
23
67
45
12
0
23
12
0
12
12
% S
% Thr:
0
0
23
56
0
0
12
12
12
0
0
34
23
34
23
% T
% Val:
0
56
23
23
34
0
0
0
0
0
0
0
0
23
12
% V
% Trp:
0
0
0
0
0
0
0
0
12
23
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _