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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IGHG4 All Species: 7.27
Human Site: T18 Identified Species: 20
UniProt: P01861 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01861 XP_002348298 327 35941 T18 L A P C S R S T S E S T A A L
Chimpanzee Pan troglodytes XP_001168435 401 43934 T54 L A P C S R S T S E G T A A L
Rhesus Macaque Macaca mulatta XP_001099592 413 44999 A62 S T S Q S T A A L G C L V K D
Dog Lupus familis XP_856442 233 24837
Cat Felis silvestris
Mouse Mus musculus P03987 398 43911 S20 G C S D T S G S S V T L G C L
Rat Rattus norvegicus P20759 326 35927 K18 L A P G T A L K S N S M V T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507984 588 64292 E209 L T P S C K E E E L S E V T V
Chicken Gallus gallus P01875 446 48155 T115 N G I P L F V T M H P P S R E
Frog Xenopus laevis NP_001083154 562 62536 T254 E P E P I K P T V E I L Q G P
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69.5 71.9 21.1 N.A. 52 63.2 N.A. 26.1 25.3 25.9 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 73.5 74.5 35.4 N.A. 64.5 78.9 N.A. 35.7 39.4 37.5 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 6.6 0 N.A. 13.3 40 N.A. 20 6.6 13.3 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 13.3 0 N.A. 33.3 46.6 N.A. 33.3 13.3 20 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 34 0 0 0 12 12 12 0 0 0 0 23 23 0 % A
% Cys: 0 12 0 23 12 0 0 0 0 0 12 0 0 12 0 % C
% Asp: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 12 % D
% Glu: 12 0 12 0 0 0 12 12 12 34 0 12 0 0 12 % E
% Phe: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % F
% Gly: 12 12 0 12 0 0 12 0 0 12 12 0 12 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % H
% Ile: 0 0 12 0 12 0 0 0 0 0 12 0 0 0 0 % I
% Lys: 0 0 0 0 0 23 0 12 0 0 0 0 0 12 0 % K
% Leu: 45 0 0 0 12 0 12 0 12 12 0 34 0 0 45 % L
% Met: 0 0 0 0 0 0 0 0 12 0 0 12 0 0 0 % M
% Asn: 12 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % N
% Pro: 0 12 45 23 0 0 12 0 0 0 12 12 0 0 12 % P
% Gln: 0 0 0 12 0 0 0 0 0 0 0 0 12 0 0 % Q
% Arg: 0 0 0 0 0 23 0 0 0 0 0 0 0 12 0 % R
% Ser: 12 0 23 12 34 12 23 12 45 0 34 0 12 0 0 % S
% Thr: 0 23 0 0 23 12 0 45 0 0 12 23 0 23 0 % T
% Val: 0 0 0 0 0 0 12 0 12 12 0 0 34 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _