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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COL2A1 All Species: 28.79
Human Site: S1154 Identified Species: 70.37
UniProt: P02458 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P02458 NP_001835.3 1487 141785 S1154 P S G D Q G A S G P A G P S G
Chimpanzee Pan troglodytes XP_509026 1487 141783 S1154 P S G D Q G A S G P A G P S G
Rhesus Macaque Macaca mulatta XP_001100739 1487 141821 S1154 P S G D Q G A S G P A G P S G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P28481 1487 141955 S1154 P S G D Q G A S G P A G P S G
Rat Rattus norvegicus P05539 1419 134551 S1086 P S G D Q G T S G P A G P S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P02457 1453 137479 S1121 A P G E Q G P S G A S G P A G
Frog Xenopus laevis Q91717 1486 142245 T1156 S A G D Q G A T G P A G P A G
Zebra Danio Brachydanio rerio A0MSJ1 1658 168231 T1297 P K G E R G I T G H S G P P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08120 1779 174282 P1326 L I G E R G L P G L A G E P G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P17139 1759 171068 P1399 R S G D N G Y P G A P G Q P G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.5 N.A. N.A. 95.2 91.8 N.A. N.A. 71.7 87 33 N.A. 35 N.A. 34.6 N.A.
Protein Similarity: 100 99.9 99.8 N.A. N.A. 97.4 93.6 N.A. N.A. 79 92.5 42 N.A. 44.8 N.A. 42.8 N.A.
P-Site Identity: 100 100 100 N.A. N.A. 100 93.3 N.A. N.A. 53.3 73.3 46.6 N.A. 40 N.A. 46.6 N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 100 93.3 N.A. N.A. 73.3 93.3 73.3 N.A. 53.3 N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 50 0 0 20 70 0 0 20 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 70 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 30 0 0 0 0 0 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 100 0 0 100 0 0 100 0 0 100 0 0 100 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 60 10 0 0 0 0 10 20 0 60 10 0 80 30 0 % P
% Gln: 0 0 0 0 70 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 10 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 60 0 0 0 0 0 60 0 0 20 0 0 50 0 % S
% Thr: 0 0 0 0 0 0 10 20 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _