KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRYAA
All Species:
22.73
Human Site:
S127
Identified Species:
62.5
UniProt:
P02489
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02489
NP_000385.1
173
19909
S127
L
P
S
N
V
D
Q
S
A
L
S
C
S
L
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
P02488
172
19774
S127
L
P
S
N
V
D
Q
S
A
L
S
C
S
L
S
Dog
Lupus familis
XP_536576
175
20048
D127
R
K
Y
R
I
P
A
D
V
D
P
L
A
I
T
Cat
Felis silvestris
Mouse
Mus musculus
P24622
196
22471
S150
L
P
S
N
V
D
Q
S
A
L
S
C
S
L
S
Rat
Rattus norvegicus
P24623
196
22429
S150
L
P
S
N
V
D
Q
S
A
L
S
C
S
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511816
173
19858
A127
L
P
S
N
V
D
Q
A
S
V
S
C
S
L
S
Chicken
Gallus gallus
P02504
173
19769
S127
L
P
A
N
V
D
Q
S
A
I
T
C
S
L
S
Frog
Xenopus laevis
NP_001079340
171
19770
D125
Y
R
L
P
S
N
M
D
Q
N
S
V
S
C
T
Zebra Danio
Brachydanio rerio
NP_694482
173
19695
S128
L
P
S
N
V
D
Q
S
A
I
T
C
T
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.6
56.5
N.A.
83.6
83.6
N.A.
85.5
83.2
76.8
73.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
98.8
74.8
N.A.
86.2
86.2
N.A.
94.8
91.9
91.3
87.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
0
N.A.
100
100
N.A.
80
80
13.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
26.6
N.A.
100
100
N.A.
100
100
26.6
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
12
12
67
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
78
0
12
0
% C
% Asp:
0
0
0
0
0
78
0
23
0
12
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
0
23
0
0
0
12
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
78
0
12
0
0
0
0
0
0
45
0
12
0
78
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
78
0
12
0
0
0
12
0
0
0
0
0
% N
% Pro:
0
78
0
12
0
12
0
0
0
0
12
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
78
0
12
0
0
0
0
0
0
% Q
% Arg:
12
12
0
12
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
67
0
12
0
0
67
12
0
67
0
78
0
78
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
23
0
12
0
23
% T
% Val:
0
0
0
0
78
0
0
0
12
12
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _