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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPTA1
All Species:
13.03
Human Site:
S618
Identified Species:
26.06
UniProt:
P02549
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02549
NP_003117.2
2419
279998
S618
K
D
I
Q
N
L
K
S
R
V
Q
K
Q
Q
V
Chimpanzee
Pan troglodytes
XP_001169940
2419
279797
S618
K
D
I
Q
N
L
K
S
R
V
Q
K
Q
Q
V
Rhesus Macaque
Macaca mulatta
XP_001117115
2420
279714
S618
K
D
T
Q
N
L
K
S
R
V
Q
K
Q
Q
V
Dog
Lupus familis
XP_537823
2573
295678
G705
K
D
P
S
N
L
Q
G
K
V
Q
K
H
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
P08032
2415
279847
S616
K
D
V
Q
N
L
K
S
R
V
Q
K
Q
Q
D
Rat
Rattus norvegicus
P16086
2472
284619
G609
K
D
P
S
N
L
Q
G
K
V
Q
K
H
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P07751
2477
285345
G609
K
D
P
S
N
L
Q
G
K
V
Q
K
H
Q
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001091958
2480
284939
G609
K
D
P
S
N
L
Q
G
K
V
Q
K
H
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13395
2415
278284
G612
L
D
P
T
N
L
N
G
K
M
Q
K
H
Q
N
Honey Bee
Apis mellifera
XP_623691
2418
278393
G613
L
D
P
T
N
L
N
G
K
V
Q
K
H
Q
N
Nematode Worm
Caenorhab. elegans
NP_508537
2427
281735
G626
L
D
P
T
N
I
R
G
K
L
Q
K
H
I
N
Sea Urchin
Strong. purpuratus
XP_785949
2410
278516
R610
K
D
P
T
N
L
Q
R
K
Q
L
K
H
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
93.9
53.5
N.A.
80.3
55.4
N.A.
N.A.
55.3
N.A.
54.6
N.A.
46.3
47.5
44
46
Protein Similarity:
100
98.8
96.9
70.2
N.A.
89.3
72.8
N.A.
N.A.
72.4
N.A.
71.8
N.A.
67
67.1
64.8
65.5
P-Site Identity:
100
100
93.3
53.3
N.A.
86.6
53.3
N.A.
N.A.
53.3
N.A.
53.3
N.A.
40
46.6
26.6
40
P-Site Similarity:
100
100
93.3
66.6
N.A.
93.3
66.6
N.A.
N.A.
66.6
N.A.
66.6
N.A.
53.3
53.3
53.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
59
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
0
% H
% Ile:
0
0
17
0
0
9
0
0
0
0
0
0
0
9
0
% I
% Lys:
75
0
0
0
0
0
34
0
67
0
0
100
0
0
0
% K
% Leu:
25
0
0
0
0
92
0
0
0
9
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
100
0
17
0
0
0
0
0
0
0
25
% N
% Pro:
0
0
67
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
34
0
0
42
0
0
9
92
0
34
84
0
% Q
% Arg:
0
0
0
0
0
0
9
9
34
0
0
0
0
0
0
% R
% Ser:
0
0
0
34
0
0
0
34
0
0
0
0
0
9
0
% S
% Thr:
0
0
9
34
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
75
0
0
0
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _