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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPTA1 All Species: 16.67
Human Site: T20 Identified Species: 33.33
UniProt: P02549 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P02549 NP_003117.2 2419 279998 T20 S G P K V L E T A E E I Q E R
Chimpanzee Pan troglodytes XP_001169940 2419 279797 T20 S G P K V L E T A E E I Q E R
Rhesus Macaque Macaca mulatta XP_001117115 2420 279714 T20 S G P K V L E T A E E I Q E R
Dog Lupus familis XP_537823 2573 295678 T107 S G V K V L E T A E D I Q E R
Cat Felis silvestris
Mouse Mus musculus P08032 2415 279847 R27 A E E I Q H R R A E V L N Q Y
Rat Rattus norvegicus P16086 2472 284619 Q20 E D I Q E R R Q Q V L D R Y H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P07751 2477 285345 Q20 E D I Q E R R Q Q V L D R Y H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001091958 2480 284939 Q20 D D I Q E R R Q Q V L D R Y R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13395 2415 278284 R21 T V E D I Q E R R E Q V L S R
Honey Bee Apis mellifera XP_623691 2418 278393 R21 N P E D I Q E R R E Q V L S R
Nematode Worm Caenorhab. elegans NP_508537 2427 281735 T28 Q E I R I L E T A D D I H Q R
Sea Urchin Strong. purpuratus XP_785949 2410 278516 R20 A E D I Q E R R D Q V L N R Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 93.9 53.5 N.A. 80.3 55.4 N.A. N.A. 55.3 N.A. 54.6 N.A. 46.3 47.5 44 46
Protein Similarity: 100 98.8 96.9 70.2 N.A. 89.3 72.8 N.A. N.A. 72.4 N.A. 71.8 N.A. 67 67.1 64.8 65.5
P-Site Identity: 100 100 100 86.6 N.A. 13.3 0 N.A. N.A. 0 N.A. 6.6 N.A. 20 20 40 0
P-Site Similarity: 100 100 100 93.3 N.A. 33.3 13.3 N.A. N.A. 13.3 N.A. 20 N.A. 46.6 46.6 73.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 25 9 17 0 0 0 0 9 9 17 25 0 0 0 % D
% Glu: 17 25 25 0 25 9 59 0 0 59 25 0 0 34 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 34 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 9 0 17 % H
% Ile: 0 0 34 17 25 0 0 0 0 0 0 42 0 0 0 % I
% Lys: 0 0 0 34 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 42 0 0 0 0 25 17 17 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % N
% Pro: 0 9 25 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 0 25 17 17 0 25 25 9 17 0 34 17 0 % Q
% Arg: 0 0 0 9 0 25 42 34 17 0 0 0 25 9 67 % R
% Ser: 34 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % S
% Thr: 9 0 0 0 0 0 0 42 0 0 0 0 0 0 0 % T
% Val: 0 9 9 0 34 0 0 0 0 25 17 17 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _