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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPTA1 All Species: 12.73
Human Site: T2214 Identified Species: 25.45
UniProt: P02549 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.73
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P02549 NP_003117.2 2419 279998 T2214 Q A M K R Q L T K I V D L G D
Chimpanzee Pan troglodytes XP_001169940 2419 279797 T2214 Q A M K R Q L T K I V D L G D
Rhesus Macaque Macaca mulatta XP_001117115 2420 279714 T2214 Q A M K R Q L T K I E D L G D
Dog Lupus familis XP_537823 2573 295678 K2364 R A M R S Q L K K I E D L G A
Cat Felis silvestris
Mouse Mus musculus P08032 2415 279847 T2210 Q A M K R H L T K I E D L G D
Rat Rattus norvegicus P16086 2472 284619 K2263 R A M R S Q L K K I E D L G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P07751 2477 285345 K2268 R A M R S Q L K K I E D L G A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001091958 2480 284939 K2271 R A M R S Q L K K I E D L G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13395 2415 278284 K2205 R A R R V D L K K I E E L G A
Honey Bee Apis mellifera XP_623691 2418 278393 K2208 R A R R Q D L K K I E D L G A
Nematode Worm Caenorhab. elegans NP_508537 2427 281735 R2217 K A N K G Q L R Q I E E K G A
Sea Urchin Strong. purpuratus XP_785949 2410 278516 K2201 R A Q K S T L K K I E D L G A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 93.9 53.5 N.A. 80.3 55.4 N.A. N.A. 55.3 N.A. 54.6 N.A. 46.3 47.5 44 46
Protein Similarity: 100 98.8 96.9 70.2 N.A. 89.3 72.8 N.A. N.A. 72.4 N.A. 71.8 N.A. 67 67.1 64.8 65.5
P-Site Identity: 100 100 93.3 60 N.A. 86.6 60 N.A. N.A. 60 N.A. 60 N.A. 40 46.6 40 53.3
P-Site Similarity: 100 100 93.3 73.3 N.A. 86.6 73.3 N.A. N.A. 73.3 N.A. 73.3 N.A. 60 66.6 60 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 67 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 17 0 0 0 0 0 84 0 0 34 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 84 17 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 0 0 0 0 0 0 0 0 100 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % I
% Lys: 9 0 0 50 0 0 0 59 92 0 0 0 9 0 0 % K
% Leu: 0 0 0 0 0 0 100 0 0 0 0 0 92 0 0 % L
% Met: 0 0 67 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 34 0 9 0 9 67 0 0 9 0 0 0 0 0 0 % Q
% Arg: 59 0 17 50 34 0 0 9 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 42 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 9 0 34 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 9 0 0 0 0 0 17 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _