KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNNC2
All Species:
4.55
Human Site:
S134
Identified Species:
8.33
UniProt:
P02585
Number Species:
12
Phosphosite Substitution
Charge Score:
0.92
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02585
NP_003270.1
160
18122
S134
V
T
D
E
E
I
E
S
L
M
K
D
G
D
K
Chimpanzee
Pan troglodytes
XP_512771
270
29312
E245
L
T
D
E
E
V
D
E
M
I
R
E
A
D
I
Rhesus Macaque
Macaca mulatta
XP_001085656
165
18786
E135
I
T
E
D
D
I
E
E
L
M
K
D
G
D
K
Dog
Lupus familis
XP_859276
159
18208
E133
I
T
E
D
D
I
E
E
L
M
K
D
G
D
K
Cat
Felis silvestris
Mouse
Mus musculus
P20801
160
18092
S134
V
T
E
E
E
I
E
S
L
M
K
D
G
D
K
Rat
Rattus norvegicus
P62161
149
16819
E124
L
T
D
E
E
V
D
E
M
I
R
E
A
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505895
171
19435
E145
I
T
E
D
D
I
E
E
L
M
K
D
G
D
K
Chicken
Gallus gallus
P02588
163
18357
D137
V
T
E
E
D
I
E
D
L
M
K
D
S
D
K
Frog
Xenopus laevis
NP_001079398
163
18351
E137
I
T
D
E
E
I
E
E
L
M
K
D
G
D
K
Zebra Danio
Brachydanio rerio
XP_001339131
161
18155
E135
V
A
E
E
D
I
D
E
L
M
A
D
A
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16305
149
16806
E124
L
T
D
E
E
V
D
E
M
I
R
E
A
D
I
Sea Urchin
Strong. purpuratus
XP_780862
149
16822
E124
L
T
D
E
E
V
D
E
M
I
R
E
A
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001151914
180
20469
E129
L
S
D
D
E
L
A
E
M
L
R
E
A
D
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.8
59.3
65
N.A.
98.7
50.6
N.A.
59.6
88.9
89.5
77
N.A.
N.A.
N.A.
50
50.6
Protein Similarity:
100
42.9
74.5
80
N.A.
99.3
68.7
N.A.
77.1
93.2
93.8
86.3
N.A.
N.A.
N.A.
68.1
68.1
P-Site Identity:
100
33.3
66.6
66.6
N.A.
93.3
33.3
N.A.
66.6
73.3
86.6
46.6
N.A.
N.A.
N.A.
33.3
33.3
P-Site Similarity:
100
80
93.3
93.3
N.A.
100
80
N.A.
93.3
86.6
93.3
66.6
N.A.
N.A.
N.A.
80
80
Percent
Protein Identity:
N.A.
44.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
64.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
8
0
0
0
8
0
47
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
54
31
39
0
39
8
0
0
0
62
0
100
0
% D
% Glu:
0
0
47
70
62
0
54
77
0
0
0
39
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
47
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
31
0
0
0
0
62
0
0
0
31
0
0
0
0
31
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
54
0
0
0
54
% K
% Leu:
39
0
0
0
0
8
0
0
62
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
39
62
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
39
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
16
0
0
0
0
8
0
0
% S
% Thr:
0
85
0
0
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
31
0
0
0
0
31
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _