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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APOA1
All Species:
6.36
Human Site:
S252
Identified Species:
12.73
UniProt:
P02647
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02647
NP_000030.1
267
30778
S252
V
L
E
S
F
K
V
S
F
L
S
A
L
E
E
Chimpanzee
Pan troglodytes
Q9GJU3
317
36083
Q293
L
V
E
D
M
Q
R
Q
W
A
G
L
V
E
K
Rhesus Macaque
Macaca mulatta
XP_001090730
572
65150
A448
Y
G
E
N
F
N
K
A
L
V
Q
Q
M
E
Q
Dog
Lupus familis
XP_536564
266
30163
S251
V
L
E
S
F
K
V
S
L
L
A
A
I
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q00623
264
30569
K249
M
L
E
T
L
K
T
K
A
Q
S
V
I
D
K
Rat
Rattus norvegicus
P04639
259
30044
K245
V
L
E
A
W
K
A
K
I
M
S
M
I
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517346
266
30607
R251
F
A
D
S
V
K
T
R
L
L
N
L
L
E
E
Chicken
Gallus gallus
P08250
264
30662
N247
R
L
T
P
Y
A
E
N
L
K
N
R
L
I
S
Frog
Xenopus laevis
NP_001079399
260
30289
N244
H
A
E
E
A
R
T
N
L
A
K
I
W
E
N
Zebra Danio
Brachydanio rerio
O42363
262
30238
T248
Y
M
E
N
V
R
T
T
F
A
Q
M
Y
E
T
Tiger Blowfish
Takifugu rubipres
NP_001027893
255
28474
K232
F
V
D
E
L
R
D
K
L
D
P
Y
A
Q
D
Fruit Fly
Dros. melanogaster
NP_996484
326
39804
P303
P
L
R
D
C
L
E
P
L
R
D
R
L
E
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.5
20.6
85
N.A.
65.1
62.9
N.A.
57.2
49.4
40.4
25.8
24.3
22.3
N.A.
N.A.
N.A.
Protein Similarity:
100
43.5
30.2
92.5
N.A.
80.5
75.6
N.A.
75.6
71.1
62.9
49.4
46.4
40.1
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
20
73.3
N.A.
26.6
40
N.A.
40
13.3
13.3
20
0
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
53.3
93.3
N.A.
60
73.3
N.A.
53.3
33.3
26.6
46.6
33.3
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
9
9
9
9
9
9
25
9
17
9
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
17
0
0
9
0
0
9
9
0
0
25
9
% D
% Glu:
0
0
67
17
0
0
17
0
0
0
0
0
0
59
34
% E
% Phe:
17
0
0
0
25
0
0
0
17
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
9
25
9
0
% I
% Lys:
0
0
0
0
0
42
9
25
0
9
9
0
0
0
17
% K
% Leu:
9
50
0
0
17
9
0
0
59
25
0
17
34
0
0
% L
% Met:
9
9
0
0
9
0
0
0
0
9
0
17
9
0
0
% M
% Asn:
0
0
0
17
0
9
0
17
0
0
17
0
0
0
9
% N
% Pro:
9
0
0
9
0
0
0
9
0
0
9
0
0
0
9
% P
% Gln:
0
0
0
0
0
9
0
9
0
9
17
9
0
9
9
% Q
% Arg:
9
0
9
0
0
25
9
9
0
9
0
17
0
0
0
% R
% Ser:
0
0
0
25
0
0
0
17
0
0
25
0
0
0
9
% S
% Thr:
0
0
9
9
0
0
34
9
0
0
0
0
0
0
9
% T
% Val:
25
17
0
0
17
0
17
0
0
9
0
9
9
0
0
% V
% Trp:
0
0
0
0
9
0
0
0
9
0
0
0
9
0
0
% W
% Tyr:
17
0
0
0
9
0
0
0
0
0
0
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _