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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APOE All Species: 0
Human Site: S112 Identified Species: 0
UniProt: P02649 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P02649 NP_000032.1 317 36154 S112 E E T R A R L S K E L Q A A Q
Chimpanzee Pan troglodytes Q9GJU3 317 36083
Rhesus Macaque Macaca mulatta Q28502 107 12364
Dog Lupus familis XP_533644 323 37206
Cat Felis silvestris
Mouse Mus musculus P08226 311 35848
Rat Rattus norvegicus P02650 312 35735
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516358 602 66481
Chicken Gallus gallus P08250 264 30662
Frog Xenopus laevis
Zebra Danio Brachydanio rerio O42364 281 31655
Tiger Blowfish Takifugu rubipres NP_001072103 276 31224
Fruit Fly Dros. melanogaster NP_996484 326 39804
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 31.5 68.1 N.A. 71.2 70.3 N.A. 26.4 20.1 N.A. 28.3 25.5 22.7 N.A. N.A. N.A.
Protein Similarity: 100 97.7 31.8 80.8 N.A. 83.2 82.6 N.A. 39 42.5 N.A. 52.3 50.4 42 N.A. N.A. N.A.
P-Site Identity: 100 0 0 0 N.A. 0 0 N.A. 0 0 N.A. 0 0 0 N.A. N.A. N.A.
P-Site Similarity: 100 0 0 0 N.A. 0 0 N.A. 0 0 N.A. 0 0 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 100 0 0 0 0 0 0 0 100 100 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 100 100 0 0 0 0 0 0 0 100 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 100 0 0 0 100 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 100 % Q
% Arg: 0 0 0 100 0 100 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % S
% Thr: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _