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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGB
All Species:
23.64
Human Site:
S173
Identified Species:
52
UniProt:
P02675
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02675
NP_005132.2
491
55928
S173
E
N
V
V
N
E
Y
S
S
E
L
E
K
H
Q
Chimpanzee
Pan troglodytes
XP_517495
491
55890
S173
E
N
V
V
N
E
Y
S
L
E
L
E
K
H
Q
Rhesus Macaque
Macaca mulatta
XP_001091998
491
55766
S173
E
N
V
V
N
E
Y
S
S
D
L
E
K
H
Q
Dog
Lupus familis
XP_853738
488
55421
S170
E
N
A
I
N
E
Y
S
S
E
L
E
K
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0E8
481
54734
S163
E
N
V
I
N
E
Y
S
S
I
L
E
D
Q
R
Rat
Rattus norvegicus
P14480
479
54217
S161
E
N
V
I
N
E
Y
S
S
I
L
E
D
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512278
431
48840
E119
I
D
E
I
Q
K
Y
E
K
I
I
L
D
N
E
Chicken
Gallus gallus
Q02020
463
52660
E149
I
L
S
E
Y
N
T
E
M
E
L
H
Y
N
Y
Frog
Xenopus laevis
P17634
438
50045
Y126
D
M
K
N
Y
Y
Q
Y
E
E
N
I
L
Y
L
Zebra Danio
Brachydanio rerio
NP_997939
485
54389
T168
G
L
V
V
D
Q
Y
T
D
S
L
E
T
Q
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781712
401
44305
G89
P
A
P
I
S
R
A
G
Q
C
D
C
N
C
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.7
83.9
N.A.
82.2
79
N.A.
30.3
62.1
30.1
53.1
N.A.
N.A.
N.A.
N.A.
28.7
Protein Similarity:
100
99.8
98.1
92.8
N.A.
91
88.5
N.A.
46.8
76.5
47.6
71
N.A.
N.A.
N.A.
N.A.
44.8
P-Site Identity:
100
93.3
93.3
86.6
N.A.
66.6
66.6
N.A.
6.6
13.3
6.6
33.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
100
93.3
N.A.
80
80
N.A.
46.6
20
20
53.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
10
0
10
0
% C
% Asp:
10
10
0
0
10
0
0
0
10
10
10
0
28
0
0
% D
% Glu:
55
0
10
10
0
55
0
19
10
46
0
64
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
37
10
% H
% Ile:
19
0
0
46
0
0
0
0
0
28
10
10
0
0
0
% I
% Lys:
0
0
10
0
0
10
0
0
10
0
0
0
37
0
10
% K
% Leu:
0
19
0
0
0
0
0
0
10
0
73
10
10
0
10
% L
% Met:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
55
0
10
55
10
0
0
0
0
10
0
10
19
10
% N
% Pro:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
10
10
0
10
0
0
0
0
28
37
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
10
0
10
0
0
55
46
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
10
0
0
0
0
10
0
0
% T
% Val:
0
0
55
37
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
19
10
73
10
0
0
0
0
10
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _