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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MBP All Species: 2.42
Human Site: Y148 Identified Species: 8.89
UniProt: P02686 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P02686 NP_001020252.1 304 33117 Y148 S Q R H G S K Y L A T A S T M
Chimpanzee Pan troglodytes P06906 171 18541 T17 H G S K Y L A T A S T M D H A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848417 196 21124 N42 A R E A S E D N E V F G E A D
Cat Felis silvestris
Mouse Mus musculus P04370 250 27149 S96 P H L I R L F S R D A P G R E
Rat Rattus norvegicus P02688 195 21484 S41 R D T G I L D S I G R F F S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P15720 174 18789 T20 S K M A S A S T T D H A R H G
Frog Xenopus laevis P87346 176 19701 D22 M A T A S T Y D H S R H G Y G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.9 N.A. 53.9 N.A. 71.7 46 N.A. N.A. 41.7 31.5 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 54.9 N.A. 57.8 N.A. 76.3 50.9 N.A. N.A. 47.7 42.4 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 N.A. 0 N.A. 0 0 N.A. N.A. 13.3 0 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 N.A. 13.3 N.A. 0 13.3 N.A. N.A. 26.6 13.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 15 0 43 0 15 15 0 15 15 15 29 0 15 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 0 0 0 29 15 0 29 0 0 15 0 15 % D
% Glu: 0 0 15 0 0 15 0 0 15 0 0 0 15 0 15 % E
% Phe: 0 0 0 0 0 0 15 0 0 0 15 15 15 0 0 % F
% Gly: 0 15 0 15 15 0 0 0 0 15 0 15 29 0 43 % G
% His: 15 15 0 15 0 0 0 0 15 0 15 15 0 29 0 % H
% Ile: 0 0 0 15 15 0 0 0 15 0 0 0 0 0 0 % I
% Lys: 0 15 0 15 0 0 15 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 15 0 0 43 0 0 15 0 0 0 0 0 0 % L
% Met: 15 0 15 0 0 0 0 0 0 0 0 15 0 0 15 % M
% Asn: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % N
% Pro: 15 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % P
% Gln: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 15 15 15 0 15 0 0 0 15 0 29 0 15 15 0 % R
% Ser: 29 0 15 0 43 15 15 29 0 29 0 0 15 15 0 % S
% Thr: 0 0 29 0 0 15 0 29 15 0 29 0 0 15 0 % T
% Val: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 15 0 15 15 0 0 0 0 0 15 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _