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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA1
All Species:
0.91
Human Site:
S37
Identified Species:
2
UniProt:
P02708
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02708
NP_000070.1
482
54546
S37
K
L
F
K
D
Y
S
S
V
V
R
P
V
E
D
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
Q47
K
L
F
S
H
Y
N
Q
F
I
R
P
V
E
N
Rhesus Macaque
Macaca mulatta
XP_001091711
457
51939
L31
E
T
R
L
V
A
K
L
F
K
D
Y
S
S
V
Dog
Lupus familis
XP_539232
575
65058
G45
P
C
S
R
E
Y
A
G
H
H
S
R
T
P
R
Cat
Felis silvestris
Mouse
Mus musculus
P04756
457
51920
L31
E
T
R
L
V
A
K
L
F
E
D
Y
S
S
V
Rat
Rattus norvegicus
P25108
457
51848
L31
E
T
R
L
V
A
K
L
F
K
D
Y
S
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514882
457
52055
L31
E
T
R
L
V
A
K
L
F
E
N
Y
N
S
V
Chicken
Gallus gallus
P09479
456
52164
L30
E
T
R
L
V
D
D
L
F
R
E
Y
S
K
V
Frog
Xenopus laevis
P05377
457
52088
L31
E
T
R
L
I
G
D
L
F
A
N
Y
N
K
V
Zebra Danio
Brachydanio rerio
Q98880
456
52082
T30
D
E
T
R
L
V
K
T
L
F
T
G
Y
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25162
519
60122
R43
D
L
L
S
N
Y
N
R
L
I
R
P
V
V
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.9
92.7
39.4
N.A.
89.4
89
N.A.
84
80.9
74.2
73.2
N.A.
38.3
N.A.
N.A.
N.A.
Protein Similarity:
100
60.3
93.3
56.1
N.A.
92.3
92.1
N.A.
89
87.5
83.1
82.9
N.A.
58.5
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
0
6.6
N.A.
0
0
N.A.
0
0
0
0
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
6.6
26.6
N.A.
6.6
6.6
N.A.
6.6
13.3
13.3
20
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
37
10
0
0
10
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
0
10
10
19
0
0
0
28
0
0
0
10
% D
% Glu:
55
10
0
0
10
0
0
0
0
19
10
0
0
19
0
% E
% Phe:
0
0
19
0
0
0
0
0
64
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
10
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
10
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
19
0
0
0
0
0
% I
% Lys:
19
0
0
10
0
0
46
0
0
19
0
0
0
19
10
% K
% Leu:
0
28
10
55
10
0
0
55
19
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
19
0
0
0
19
0
19
10
19
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
28
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
55
19
0
0
0
10
0
10
28
10
0
0
10
% R
% Ser:
0
0
10
19
0
0
10
10
0
0
10
0
37
37
0
% S
% Thr:
0
55
10
0
0
0
0
10
0
0
10
0
10
0
0
% T
% Val:
0
0
0
0
46
10
0
0
10
10
0
0
28
10
55
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
37
0
0
0
0
0
55
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _