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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRP All Species: 20.91
Human Site: S138 Identified Species: 57.5
UniProt: P02741 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P02741 NP_000558.2 224 25039 S138 G K P R V R K S L K K G Y T V
Chimpanzee Pan troglodytes XP_513917 224 25034 S138 G K P R V R K S L K K G Y T V
Rhesus Macaque Macaca mulatta XP_001117250 224 25212 S138 G K P R A R K S L K R G Y T V
Dog Lupus familis XP_545746 318 35124 S232 G K P M V R A S L R R G Y T V
Cat Felis silvestris
Mouse Mus musculus P14847 225 25342 S139 G K A K V R K S L H K G Y T V
Rat Rattus norvegicus P48199 230 25449 S137 G K P R V R K S L Q K G Y I V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521709 287 31507 I183 D P P D S K H I C A T W E S A
Chicken Gallus gallus
Frog Xenopus laevis Q07203 238 27066 V136 G K L Y P R T V S K K A S S I
Zebra Danio Brachydanio rerio NP_001108373 222 24940 V137 G Q R S L H Q V Y R Q G Y L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 91 43 N.A. 69.7 64.7 N.A. 38.6 N.A. 38.2 36.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 94.6 53.1 N.A. 82.2 76 N.A. 49.8 N.A. 55 56.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 73.3 N.A. 80 86.6 N.A. 6.6 N.A. 33.3 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 93.3 N.A. 20 N.A. 46.6 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 12 0 12 0 0 12 0 12 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % C
% Asp: 12 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 89 0 0 0 0 0 0 0 0 0 0 78 0 0 0 % G
% His: 0 0 0 0 0 12 12 0 0 12 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 12 0 0 0 0 0 12 23 % I
% Lys: 0 78 0 12 0 12 56 0 0 45 56 0 0 0 0 % K
% Leu: 0 0 12 0 12 0 0 0 67 0 0 0 0 12 0 % L
% Met: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 12 67 0 12 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 12 0 0 0 0 12 0 0 12 12 0 0 0 0 % Q
% Arg: 0 0 12 45 0 78 0 0 0 23 23 0 0 0 0 % R
% Ser: 0 0 0 12 12 0 0 67 12 0 0 0 12 23 0 % S
% Thr: 0 0 0 0 0 0 12 0 0 0 12 0 0 56 0 % T
% Val: 0 0 0 0 56 0 0 23 0 0 0 0 0 0 67 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % W
% Tyr: 0 0 0 12 0 0 0 0 12 0 0 0 78 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _