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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRP
All Species:
23.33
Human Site:
Y72
Identified Species:
64.17
UniProt:
P02741
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02741
NP_000558.2
224
25039
Y72
R
G
Y
S
I
F
S
Y
A
T
K
R
Q
D
N
Chimpanzee
Pan troglodytes
XP_513917
224
25034
Y72
R
G
Y
S
I
F
S
Y
A
T
K
R
Q
D
N
Rhesus Macaque
Macaca mulatta
XP_001117250
224
25212
Y72
R
G
Y
S
I
F
S
Y
A
T
K
R
Q
N
N
Dog
Lupus familis
XP_545746
318
35124
Y166
R
P
H
S
L
F
S
Y
A
T
K
S
Q
S
N
Cat
Felis silvestris
Mouse
Mus musculus
P14847
225
25342
Y73
R
S
F
S
V
F
S
Y
A
T
K
K
N
S
N
Rat
Rattus norvegicus
P48199
230
25449
Y71
R
S
F
S
I
F
S
Y
A
T
K
T
S
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521709
287
31507
G82
P
Q
E
A
E
G
R
G
C
L
G
Q
S
F
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Q07203
238
27066
T70
H
S
L
L
S
L
A
T
S
N
P
L
Q
D
N
Zebra Danio
Brachydanio rerio
NP_001108373
222
24940
Y70
R
E
I
I
L
F
A
Y
R
T
P
D
D
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
91
43
N.A.
69.7
64.7
N.A.
38.6
N.A.
38.2
36.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
94.6
53.1
N.A.
82.2
76
N.A.
49.8
N.A.
55
56.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
66.6
N.A.
60
66.6
N.A.
0
N.A.
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
80
73.3
N.A.
13.3
N.A.
33.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
23
0
67
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
12
12
45
0
% D
% Glu:
0
12
12
0
12
0
0
0
0
0
0
0
0
0
12
% E
% Phe:
0
0
23
0
0
78
0
0
0
0
0
0
0
23
0
% F
% Gly:
0
34
0
0
0
12
0
12
0
0
12
0
0
0
0
% G
% His:
12
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
12
45
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
67
12
0
0
0
% K
% Leu:
0
0
12
12
23
12
0
0
0
12
0
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
0
12
12
78
% N
% Pro:
12
12
0
0
0
0
0
0
0
0
23
0
0
0
0
% P
% Gln:
0
12
0
0
0
0
0
0
0
0
0
12
56
0
0
% Q
% Arg:
78
0
0
0
0
0
12
0
12
0
0
34
0
0
0
% R
% Ser:
0
34
0
67
12
0
67
0
12
0
0
12
23
23
0
% S
% Thr:
0
0
0
0
0
0
0
12
0
78
0
12
0
0
0
% T
% Val:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
34
0
0
0
0
78
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _