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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APCS
All Species:
20
Human Site:
S166
Identified Species:
48.89
UniProt:
P02743
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02743
NP_001630.1
223
25387
S166
Y
G
G
K
F
D
R
S
Q
S
F
V
G
E
I
Chimpanzee
Pan troglodytes
XP_513916
223
25403
S166
Y
G
G
K
F
D
R
S
Q
S
F
V
G
E
I
Rhesus Macaque
Macaca mulatta
XP_001117234
223
25296
S166
Y
G
G
K
F
D
K
S
Q
S
F
V
G
E
I
Dog
Lupus familis
XP_545746
318
35124
N261
F
G
G
G
F
D
K
N
Q
S
L
V
G
D
I
Cat
Felis silvestris
Mouse
Mus musculus
P12246
224
26228
S167
Y
G
G
G
F
Q
R
S
Q
S
F
V
G
E
F
Rat
Rattus norvegicus
P23680
228
26157
T167
Y
G
G
G
F
D
K
T
Q
S
F
V
G
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521709
287
31507
G218
G
Y
K
V
G
A
G
G
Q
M
I
L
G
Q
E
Chicken
Gallus gallus
NP_001034653
227
25642
Y166
Y
G
G
G
F
D
V
Y
N
S
F
T
G
E
M
Frog
Xenopus laevis
Q07203
238
27066
D165
F
G
G
G
F
N
I
D
Q
S
F
V
G
E
I
Zebra Danio
Brachydanio rerio
NP_001020468
222
24929
A165
Y
V
G
S
F
N
A
A
Q
S
F
V
G
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
90.5
34.2
N.A.
68.7
70.1
N.A.
41.4
45.8
36.1
37.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
95
48.1
N.A.
81.2
82
N.A.
54
63.4
54.2
56
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
60
N.A.
80
80
N.A.
13.3
60
66.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
80
93.3
N.A.
26.6
66.6
80
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
60
0
10
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
10
% E
% Phe:
20
0
0
0
90
0
0
0
0
0
80
0
0
0
10
% F
% Gly:
10
80
90
50
10
0
10
10
0
0
0
0
100
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
70
% I
% Lys:
0
0
10
30
0
0
30
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
20
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
90
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
30
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
0
0
40
0
90
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% T
% Val:
0
10
0
10
0
0
10
0
0
0
0
80
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
70
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _