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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C1QA All Species: 23.33
Human Site: S186 Identified Species: 57.04
UniProt: P02745 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P02745 NP_057075.1 245 26017 S186 S R G Q V R R S L G F C D T T
Chimpanzee Pan troglodytes XP_001166821 245 25953 S186 S R G Q V R R S L G F C D T T
Rhesus Macaque Macaca mulatta XP_001101837 245 26006 S186 S R G Q V R R S L G F C D T T
Dog Lupus familis XP_535367 245 25863 S186 G R A Q I R R S L G F C D T N
Cat Felis silvestris
Mouse Mus musculus P98086 245 25968 S186 S G G Q P R D S L S F S N T N
Rat Rattus norvegicus P31720 245 25899 S186 S R G Q P R N S L G F C D T N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520350 241 26139 T182 K A G R S K S T L G F C D S N
Chicken Gallus gallus XP_417654 243 25515 C186 A E R V V S F C D N N S R N I
Frog Xenopus laevis NP_001085836 236 24733 A178 K A Q K S K M A T F C D Q A N
Zebra Danio Brachydanio rerio A5PN28 489 50773 T430 N G I R K L R T R D S L Y G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 91 80 N.A. 70.6 73.4 N.A. 46.5 47.7 36.7 22.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 96.3 88.5 N.A. 81.6 85.7 N.A. 58.3 62.4 56.3 31.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 73.3 N.A. 53.3 80 N.A. 40 6.6 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 60 80 N.A. 66.6 13.3 20 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 20 10 0 0 0 0 10 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 10 60 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 10 10 0 10 60 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 10 70 0 0 0 0 % F
% Gly: 10 20 60 0 0 0 0 0 0 60 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 20 0 0 10 10 20 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 10 0 0 70 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 10 0 0 10 10 0 10 10 50 % N
% Pro: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 60 0 0 0 0 0 0 0 0 10 0 10 % Q
% Arg: 0 50 10 20 0 60 50 0 10 0 0 0 10 0 0 % R
% Ser: 50 0 0 0 20 10 10 60 0 10 10 20 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 20 10 0 0 0 0 60 30 % T
% Val: 0 0 0 10 40 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _