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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GC
All Species:
27.58
Human Site:
Y223
Identified Species:
67.41
UniProt:
P02774
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02774
NP_000574.2
474
52964
Y223
S
N
R
V
C
S
Q
Y
A
A
Y
G
E
K
K
Chimpanzee
Pan troglodytes
XP_517242
474
52917
Y223
S
N
R
V
C
S
Q
Y
A
A
Y
G
E
K
K
Rhesus Macaque
Macaca mulatta
XP_001104833
474
53064
Y223
S
N
R
V
C
S
Q
Y
A
A
Y
G
E
K
K
Dog
Lupus familis
XP_532404
474
52956
Y223
S
N
R
I
C
S
Q
Y
A
A
Y
G
K
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P21614
476
53582
Y223
S
N
R
V
C
S
Q
Y
A
A
Y
G
K
E
K
Rat
Rattus norvegicus
P04276
476
53526
Y223
S
N
R
V
C
S
Q
Y
A
A
Y
G
K
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511847
587
65354
Y328
S
N
S
M
C
S
R
Y
A
A
Y
G
K
K
F
Chicken
Gallus gallus
NP_990213
484
53668
L224
S
N
R
A
C
S
R
L
A
A
Y
G
K
D
K
Frog
Xenopus laevis
P14872
607
70364
I225
K
Q
H
H
F
C
W
I
L
D
N
F
P
E
K
Zebra Danio
Brachydanio rerio
NP_001002568
464
51739
S217
N
I
F
L
R
F
L
S
H
V
C
N
N
Q
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
93.6
82.2
N.A.
77.5
76.8
N.A.
48.5
50.2
22.7
31
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97
91.1
N.A.
89
89.9
N.A.
62.3
71.9
39.7
51
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
86.6
86.6
N.A.
66.6
66.6
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
80
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
80
80
0
0
0
0
0
% A
% Cys:
0
0
0
0
80
10
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
30
40
0
% E
% Phe:
0
0
10
0
10
10
0
0
0
0
0
10
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
80
0
0
0
% G
% His:
0
0
10
10
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
10
0
10
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
50
40
80
% K
% Leu:
0
0
0
10
0
0
10
10
10
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
80
0
0
0
0
0
0
0
0
10
10
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
10
0
0
0
0
60
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
70
0
10
0
20
0
0
0
0
0
0
0
0
% R
% Ser:
80
0
10
0
0
80
0
10
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
50
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
80
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _